Gene: RAP2A
Official Full Name: RAP2A, member of RAS oncogene familyprovided by HGNC
Gene Summary: Enables GTPase activity; guanyl ribonucleotide binding activity; and magnesium ion binding activity. Involved in several processes, including microvillus assembly; positive regulation of protein autophosphorylation; and regulation of dendrite morphogenesis. Acts upstream of or within establishment of protein localization. Located in plasma membrane and recycling endosome membrane. Is active in Schaffer collateral - CA1 synapse. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35700 | RAP2A Knockout cell line (HeLa) | Human | RAP2A | 1:3~1:6 | Negative | Online Inquiry |
KO35701 | RAP2A Knockout cell line (HCT 116) | Human | RAP2A | 1:2~1:4 | Negative | Online Inquiry |
KO35702 | RAP2A Knockout cell line (HEK293) | Human | RAP2A | 1:3~1:6 | Negative | Online Inquiry |
KO35703 | RAP2A Knockout cell line (A549) | Human | RAP2A | 1:3~1:4 | Negative | Online Inquiry |
RAP2A Gene Knockout Cell Lines are specially engineered cell lines that have been genetically modified to lack the RAP2A gene, which encodes a small GTPase involved in the regulation of various cellular processes, including cell adhesion, motility, and proliferation. These knockout cell lines serve as essential tools for investigating the biological functions attributed to the RAP2A protein, enabling researchers to elucidate its role in signaling pathways and potential implications in disease states such as cancer, cardiovascular diseases, and various neurodegenerative disorders.
The primary function of RAP2A Gene Knockout Cell Lines is to facilitate the study of gene function by providing a context in which the effects of the absence of RAP2A can be assessed. By employing CRISPR-Cas9 technology for the knockout process, these cell lines allow scientists to explore compensatory mechanisms that may arise due to the loss of RAP2A, making them invaluable for dissecting the complexities of cellular signaling networks. This functionality is vital for drug discovery and the development of targeted therapies.
The scientific importance of RAP2A Gene Knockout Cell Lines is evidenced by their widespread applications in both research and clinical settings. They are instrumental in studying developmental biology, tumor biology, and the mechanisms of drug resistance. Furthermore, they can be utilized to screen potential therapeutic compounds that target RAP2A-associated pathways, thereby providing insights that could lead to innovative treatment strategies.
In comparison to alternative models, such as RNA interference or overexpression systems, RAP2A Gene Knockout Cell Lines offer a more permanent and comprehensive approach to gene manipulation. This permanence enhances reproducibility and allows for long-term studies on the cellular and physiological effects of the gene knockout, which is particularly beneficial for understanding chronic conditions.
For researchers and clinicians, the value of RAP2A Gene Knockout Cell Lines lies in their ability to provide definitive insights into the function of RAP2A, ultimately contributing to the advancement of scientific knowledge and therapeutic development. Our company prides itself on its commitment to quality and innovation in biological research tools, ensuring that our products meet the rigorous standards necessary for cutting-edge research.
Please note that all services are for research use only. Not intended for any clinical use.
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