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RANBP9 Knockout Cell Lines

Gene: RANBP9

Official Full Name: RAN binding protein 9provided by HGNC

Gene Summary: This gene encodes a protein that binds RAN, a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The protein encoded by this gene has also been shown to interact with several other proteins, including met proto-oncogene, homeodomain interacting protein kinase 2, androgen receptor, and cyclin-dependent kinase 11. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32349 RANBP9 Knockout cell line (HeLa) Human RANBP9 1:3~1:6 Negative Online Inquiry
KO32350 RANBP9 Knockout cell line (HCT 116) Human RANBP9 1:2~1:4 Negative Online Inquiry
KO32351 RANBP9 Knockout cell line (HEK293) Human RANBP9 1:3~1:6 Negative Online Inquiry
KO32352 RANBP9 Knockout cell line (A549) Human RANBP9 1:3~1:4 Negative Online Inquiry

Background

RANBP9 Gene Knockout Cell Lines are genetically engineered models designed to silence the RANBP9 gene, which is implicated in numerous cellular processes including cell proliferation, apoptosis, and migration. These cell lines are invaluable tools for researchers aimed at elucidating the biological roles of RANBP9 in various pathological conditions, particularly cancer and neurodegenerative diseases. By providing a system where the effects of RANBP9 loss can be meticulously studied, these knockout cell lines facilitate a deeper understanding of molecular pathways that could lead to novel therapeutic strategies.

The mechanism underlying the functionality of RANBP9 gene knockout cell lines involves the complete disruption of the RANBP9 protein production. This disruption enables researchers to observe the resultant phenotypic changes in cellular behavior, such as altered signaling pathways, modified gene expression profiles, and changes in cellular morphology. Utilizing advanced techniques like CRISPR/Cas9 gene editing ensures precise gene targeting, yielding consistently reliable results.

The scientific importance of RANBP9 Gene Knockout Cell Lines is evident in their diverse applications within both research and clinical settings. They serve as a foundation for investigating the gene's role in tumorigenesis, drug resistance, and cellular stress responses. These models can also be used to screen potential therapeutics and study the efficacy of new compounds aimed at modulating RANBP9-related pathways.

In comparison to traditional methods, such as RNA interference, our RANBP9 knockout cell lines offer distinct advantages, including permanent gene knockout, greater specificity, and ease of use in various experimental contexts. Researchers can obtain consistent and reproducible results that are crucial for advancing scientific knowledge.

These knockout cell lines represent a significant resource for both academic and industry laboratories, empowering scientists to explore unanswered questions in cellular biology and develop innovative solutions to pressing health challenges. Our company’s extensive expertise in gene editing and commitment to providing high-quality biological products ensures that our RANBP9 Gene Knockout Cell Lines meet the rigorous standards needed for impactful research.

Please note that all services are for research use only. Not intended for any clinical use.

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