Home / RALGDS Knockout Cell Lines

RALGDS Knockout Cell Lines

Gene: RALGDS

Official Full Name: ral guanine nucleotide dissociation stimulatorprovided by HGNC

Gene Summary: Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases (see MIM 190020) that participate in signaling for a variety of cellular processes.[supplied by OMIM, Nov 2010]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08924 RALGDS Knockout cell line (HeLa) Human RALGDS 1:3~1:6 Negative Online Inquiry
KO08925 RALGDS Knockout cell line (HCT 116) Human RALGDS 1:2~1:4 Negative Online Inquiry
KO08926 RALGDS Knockout cell line (HEK293) Human RALGDS 1:3~1:6 Negative Online Inquiry
KO08927 RALGDS Knockout cell line (A549) Human RALGDS 1:3~1:4 Negative Online Inquiry

Background

RALGDS Gene Knockout Cell Lines are specially engineered cellular models that enable the precise investigation of RALGDS gene function through the targeted disruption of its coding sequence. By utilizing CRISPR/Cas9 technology, these cell lines exhibit a complete knockout of the RALGDS gene, eliminating the production of its protein product. This specificity allows researchers to study the biological pathways influenced by RALGDS without the confounding effects of gene expression, thus providing clarity in functional assays and biological investigations.

The functionality of these cell lines hinges on their ability to act as a tool for dissecting signaling cascades in various physiological and pathological contexts. RALGDS is implicated in the regulation of Ras signaling pathways, thereby influencing cellular processes such as proliferation, differentiation, and survival. Consequently, using RALGDS knockout lines allows for the exploration of these mechanisms in cancer research, neurology, and developmental biology, facilitating the identification of potential therapeutic targets and informing drug development strategies.

What sets RALGDS Gene Knockout Cell Lines apart from alternative models is their ease of use and reproducibility across different experimental setups. Unlike transient transfection methods, which can result in inconsistent gene expression levels, these knockout lines provide a stable environment for long-term studies, delivering consistent data and higher confidence in experimental outcomes. Moreover, the specific knockout achieves a stronger loss-of-function phenotype, making it an excellent choice for researchers focused on understanding RALGDS's role in various diseases.

Researchers and clinicians will find immense value in RALGDS Gene Knockout Cell Lines as they simplify complex biological studies and accelerate the discovery of impactful insights within the realm of gene function and regulation. The accuracy of these models combined with their potential for high-throughput applications bolsters their relevance in contemporary cellular biology research.

Our company is dedicated to providing top-tier biological products and solutions tailored for the scientific community. With expertise in genetic engineering and a commitment to quality, we enable researchers to unlock the secrets of gene function and enhance their research capabilities.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.