Gene: RADX
Official Full Name: RPA1 related single stranded DNA binding protein, X-linkedprovided by HGNC
Gene Summary: Enables single-stranded DNA binding activity. Involved in negative regulation of double-strand break repair via homologous recombination. Located in nuclear speck and replication fork. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14725 | RADX Knockout cell line (HCT 116) | Human | RADX | 1:2~1:4 | Negative | Online Inquiry |
KO14726 | RADX Knockout cell line (HEK293) | Human | RADX | 1:3~1:6 | Negative | Online Inquiry |
RADX Gene Knockout Cell Lines are a series of genetically altered cell lines designed to facilitate gene knockout studies, allowing researchers to investigate the functions of specific genes in various biological contexts. By utilizing CRISPR-Cas9 technology, RADX provides researchers with precise, efficient, and reproducible gene editing capabilities, permitting the selective inactivation of target genes to elucidate their roles in cellular processes, disease models, and therapeutic responses.
The primary function of RADX Gene Knockout Cell Lines lies in their ability to produce loss-of-function models that replicate human disease phenotypes. This technology harnesses the power of the CRISPR-Cas9 system to generate mutations in genomic DNA at specific loci, effectively disrupting gene function. Researchers can employ these cell lines to investigate gene function in the context of cancer biology, drug resistance mechanisms, and metabolic disorders, thereby enhancing our understanding of complex biological systems.
Scientifically, the application of RADX Gene Knockout Cell Lines is profound, significantly advancing fields such as genetics, molecular biology, and pharmacology. Their versatility enables applications ranging from basic research to translational medicine, where they serve as vital tools for drug discovery and the development of novel therapies.
What sets RADX apart is the validated specificity and efficiency of each knockout model, compared to traditional knockout methods that are often cumbersome and less precise. Furthermore, these cell lines come with extensive documentation of genomic alterations, ensuring researchers can rely on accurate data in their experimental designs.
For researchers and clinicians alike, the value of RADX Gene Knockout Cell Lines lies not only in their ease of use but also in their potential to reveal critical insights into gene function that can lead to breakthroughs in understanding and treating diseases.
With years of expertise in biotechnological development and a commitment to advancing research methodologies, our company is dedicated to providing innovative tools like RADX Gene Knockout Cell Lines to support the scientific community in unlocking the complexities of gene function and contributing to the future of healthcare.
Please note that all services are for research use only. Not intended for any clinical use.
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