Gene: RAD51AP1
Official Full Name: RAD51 associated protein 1provided by HGNC
Gene Summary: Enables nucleic acid binding activity. Involved in DNA repair; cellular response to ionizing radiation; and positive regulation of DNA recombination. Located in chromatin and nucleus. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31649 | RAD51AP1 Knockout cell line (HeLa) | Human | RAD51AP1 | 1:3~1:6 | Negative | Online Inquiry |
KO31650 | RAD51AP1 Knockout cell line (HCT 116) | Human | RAD51AP1 | 1:2~1:4 | Negative | Online Inquiry |
KO31651 | RAD51AP1 Knockout cell line (HEK293) | Human | RAD51AP1 | 1:3~1:6 | Negative | Online Inquiry |
KO31652 | RAD51AP1 Knockout cell line (A549) | Human | RAD51AP1 | 1:3~1:4 | Negative | Online Inquiry |
RAD51AP1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the RAD51AP1 gene, which plays a pivotal role in DNA repair and homologous recombination processes. This product involves a targeted deletion of the RAD51AP1 gene, enabling researchers to investigate its function and interactions more comprehensively. By utilizing these knockout cell lines, scientists can elucidate the underlying mechanisms that contribute to genomic stability and repair pathways, offering insights into cellular responses to DNA damage.
The primary function of RAD51AP1 is to assist in DNA double-strand break repair by enhancing the activity of RAD51, a crucial protein in the homologous recombination repair pathway. The knockout of RAD51AP1 allows for an in-depth analysis of the resultant phenotypic changes, such as altered DNA repair efficiency and increased sensitivity to DNA-damaging agents, which are vital for developing targeted therapies and understanding cancer biology. Furthermore, these cell lines can be used to screen for potential pharmacological compounds that may influence DNA repair processes, thereby opening avenues for novel therapeutic interventions.
In both research and clinical settings, RAD51AP1 Gene Knockout Cell Lines serve as an invaluable tool for studying genetic predispositions to diseases, particularly in cancer. They enable the examination of the functional consequences of RAD51AP1 disruption in a controlled environment, making them essential for understanding why certain tumors may be more susceptible to specific therapies.
What sets these knockout cell lines apart from other alternatives is their specificity and reliability in simulating the effects of RAD51AP1 loss. Their optimized performance in a range of experimental conditions supports reproducibility, which is crucial for robust scientific conclusions. Moreover, the availability of validated cell lines means that researchers can initiate experiments with confidence, knowing they have a solid foundation for their investigations.
Our company specializes in the development of high-quality biological products and has a proven track record in genetic engineering. With expertise in creating customized cell lines, we are committed to supporting the scientific community in their quest for knowledge and innovation, ensuring that products like our RAD51AP1 Gene Knockout Cell Lines not only advance research endeavors but also contribute to breakthroughs in clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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