Gene: RABIF
Official Full Name: RAB interacting factorprovided by HGNC
Gene Summary: This gene encodes a member of the SCE4/YPT1/RAB family of small GTP-binding proteins that are involved in the regulation of intracellular vesicular transport. This protein stimulates GTP-GDP exchange in SEC4, and to a lesser extent in YPT1 and RAB3A, and may play a general role in vesicular transport. [provided by RefSeq, Oct 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35692 | RABIF Knockout cell line (HeLa) | Human | RABIF | 1:3~1:6 | Negative | Online Inquiry |
KO35693 | RABIF Knockout cell line (HCT 116) | Human | RABIF | 1:2~1:4 | Negative | Online Inquiry |
KO35694 | RABIF Knockout cell line (HEK293) | Human | RABIF | 1:3~1:6 | Negative | Online Inquiry |
KO35695 | RABIF Knockout cell line (A549) | Human | RABIF | 1:3~1:4 | Negative | Online Inquiry |
RABIF Gene Knockout Cell Lines are specifically engineered cellular models created to facilitate the study of gene function and the underlying mechanisms of disease associated with the RABIF gene. These cell lines are generated through CRISPR-Cas9 technology, which allows for precise editing of the genome, resulting in a complete knockout of RABIF expression. This technique creates well-characterized and reproducible cellular environments that are essential for researchers investigating the role of RABIF in cellular processes such as vesicle trafficking, signal transduction, and cellular homeostasis.
The key functions of RABIF Gene Knockout Cell Lines lie in their ability to serve as a reliable platform for assays that explore the phenotypic consequences of RABIF loss. Researchers can utilize these knockout lines to dissect the signaling pathways affected by RABIF, assess cellular responses to various stimuli, and better understand the gene's implications in oncogenesis or infectious diseases. Their application extends to drug discovery initiatives, where identifying potential therapeutic targets necessitates a clear understanding of gene function in a pathophysiological context.
One significant advantage of RABIF Gene Knockout Cell Lines is their specificity and ease of use compared to other gene-editing methodologies, such as RNA interference or older knockout technologies, which may have off-target effects or incomplete gene silencing. Additionally, these cell lines are accompanied by thorough validation and quality control measures, ensuring that researchers work with robust and dependable models.
For scientists, clinicians, and pharmaceutical developers, the RABIF Gene Knockout Cell Lines are invaluable tools that aid in elucidating the complexities of gene regulation and disease mechanisms. By providing a clear picture of RABIF's roles, these cell lines empower users to draw meaningful conclusions that drive innovation in therapeutic research.
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