Gene: RABGAP1L
Official Full Name: RAB GTPase activating protein 1 likeprovided by HGNC
Gene Summary: Enables GTPase activator activity and small GTPase binding activity. Acts upstream of or within regulation of protein localization. Located in several cellular components, including Golgi apparatus; cilium; and early endosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32539 | RABGAP1L Knockout cell line (HeLa) | Human | RABGAP1L | 1:3~1:6 | Negative | Online Inquiry |
KO32540 | RABGAP1L Knockout cell line (HCT 116) | Human | RABGAP1L | 1:2~1:4 | Negative | Online Inquiry |
KO32541 | RABGAP1L Knockout cell line (HEK293) | Human | RABGAP1L | 1:3~1:6 | Negative | Online Inquiry |
KO32542 | RABGAP1L Knockout cell line (A549) | Human | RABGAP1L | 1:3~1:4 | Negative | Online Inquiry |
RABGAP1L Gene Knockout Cell Lines are specialized cellular models designed to study the functional role of the RAB GTPase-activating protein 1-like (RABGAP1L) gene by genetically disabling it through knockout techniques. This innovative product allows researchers to investigate the gene's impact on cellular processes, particularly those involved in membrane trafficking, cell signaling, and cytoskeletal dynamics. The RABGAP1L protein is known to modulate RAB GTPases, which are critical regulators of vesicle trafficking, thereby influencing numerous biological pathways and cellular functions.
These knockout cell lines serve as powerful tools in elucidating the mechanistic underpinnings of diseases associated with dysfunctional RAB signaling, including cancer and neurological disorders. By providing a controlled environment where the specific gene is absent, researchers can observe the resultant phenotypic changes, analyze downstream effects, and identify potential therapeutic targets. This is particularly vital in drug development and the quest for novel therapies.
One of the significant advantages of the RABGAP1L Gene Knockout Cell Lines is that they enable high-throughput screening of compounds, thereby facilitating rapid assessment of drug efficacy and safety. Compared to standard cell lines, these knockout models deliver greater specificity and relevance for studies focused on RAB-related pathways, minimizing the confounding effects often seen in non-targeted cell lines.
The value of RABGAP1L Gene Knockout Cell Lines extends beyond basic research; they are also invaluable for translational studies within clinical settings, providing insights that may lead to improved diagnostic and prognostic biomarkers. By utilizing these cell lines, researchers and clinicians can accelerate their understanding of RABGAP1L's role in disease biology and develop innovative therapeutic strategies.
Our company prides itself on being at the forefront of genetic research tools, offering products that are not only rigorously validated but also backed by extensive scientific expertise. Our commitment to quality and innovation ensures that researchers have access to resources that significantly enhance the impact of their work in the life sciences field.
Please note that all services are for research use only. Not intended for any clinical use.
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