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RABGAP1 Knockout Cell Lines

Gene: RABGAP1

Official Full Name: RAB GTPase activating protein 1provided by HGNC

Gene Summary: Enables GTPase activator activity and small GTPase binding activity. Located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29033 RABGAP1 Knockout cell line (HeLa) Human RABGAP1 1:3~1:6 Negative Online Inquiry
KO29034 RABGAP1 Knockout cell line (HCT 116) Human RABGAP1 1:2~1:4 Negative Online Inquiry
KO29035 RABGAP1 Knockout cell line (HEK293) Human RABGAP1 1:3~1:6 Negative Online Inquiry
KO29036 RABGAP1 Knockout cell line (A549) Human RABGAP1 1:3~1:4 Negative Online Inquiry

Background

RABGAP1 Gene Knockout Cell Lines are specialized cell lines engineered to disrupt the expression of the RABGAP1 gene, which encodes a GTPase-activating protein involved in the regulation of Rab family proteins crucial for intracellular trafficking. The knockout of this gene creates a system for researchers to elucidate the biological roles and pathways influenced by RABGAP1. By effectively silencing the gene, these cell lines enable the study of its function in cellular processes such as endocytosis, vesicle transport, and signal transduction.

The mechanism of action relies on advanced gene-editing technologies, such as CRISPR-Cas9, which introduce precise mutations into the genomic sequence of RABGAP1, rendering it inactive. This targeted approach allows for the generation of specific phenotypic changes that can be analyzed to understand the gene's contributions to various physiological and pathological conditions. In research settings, RABGAP1 knockout cell lines have significant implications, including the exploration of cancer biology, neurodegenerative diseases, and metabolic disorders, providing valuable insights into potential therapeutic targets.

What sets RABGAP1 Gene Knockout Cell Lines apart from traditional wild-type models is their capacity to exhibit altered signaling pathways and cellular behaviors, which can be directly linked to the absence of RABGAP1. This unique system affords researchers a powerful tool to dissect molecular mechanisms and develop new strategies for intervention. Furthermore, the ability to perform comparative studies on RABGAP1 knockout versus wild-type cells enhances the quality and robustness of experimental data.

By utilizing RABGAP1 Gene Knockout Cell Lines, researchers and clinicians can access cutting-edge tools that facilitate groundbreaking discoveries, ultimately leading to innovations in treatment and drug development. Our company specializes in the production of high-quality biological research tools, ensuring that customers receive rigorously validated and expertly crafted products tailored for advancing scientific knowledge and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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