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RAB6B Knockout Cell Lines

Gene: RAB6B

Official Full Name: RAB6B, member RAS oncogene familyprovided by HGNC

Gene Summary: Enables myosin V binding activity. Involved in Golgi organization and protein localization to Golgi membrane. Located in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO06494 RAB6B Knockout cell line (HeLa) Human RAB6B 1:3~1:6 Negative Online Inquiry
KO06495 RAB6B Knockout cell line (HCT 116) Human RAB6B 1:2~1:4 Negative Online Inquiry
KO06496 RAB6B Knockout cell line (HEK293) Human RAB6B 1:3~1:6 Negative Online Inquiry
KO06497 RAB6B Knockout cell line (A549) Human RAB6B 1:3~1:4 Negative Online Inquiry

Background

RAB6B Gene Knockout Cell Lines are genetically engineered cellular models designed to precisely disrupt the RAB6B gene, an essential component of the RAB family of small GTPases involved in intracellular transport processes. These cell lines allow researchers to investigate the biological functions of RAB6B by observing the phenotypic outcomes of its absence, particularly in vesicular trafficking, cell signaling, and cytoskeletal organization. By employing CRISPR-Cas9 technology, RAB6B gene knockout is achieved with high specificity, minimizing off-target effects and ensuring reliable results.

The key functions of these cell lines include the ability to elucidate the role of RAB6B in various cellular processes and disease mechanisms. By studying these cell lines, researchers can unravel how the loss of RAB6B impacts cellular dynamics and identify potential pathways influenced by this gene, contributing to a deeper understanding of disorders such as cancer, neurodegeneration, and metabolic diseases.

The scientific importance of RAB6B Gene Knockout Cell Lines extends to both basic and translational research, as they serve as powerful tools for drug discovery and therapeutic development. By examining the effects of potential treatments on these knockout models, researchers can better evaluate the pathways influenced by RAB6B, potentially leading to novel interventions.

What sets our RAB6B Gene Knockout Cell Lines apart from alternative models is the meticulous validation process that ensures authenticity and functionality of the gene deletion. Furthermore, our product offers enhanced reproducibility and standardized protocols, making it the optimal choice for time-sensitive research environments.

Researchers and clinicians seeking to investigate the functionalities of RAB6B and its implications in disease will find immense value in these cell lines. With our commitment to quality and innovation, our company stands as a trusted provider of advanced biological tools, supporting the scientific community in uncovering critical insights into gene function and therapeutic targets.

Please note that all services are for research use only. Not intended for any clinical use.

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