Gene: RAB5IF
Official Full Name: RAB5 interacting factorprovided by HGNC
Gene Summary: Involved in mitochondrial respirasome assembly and multi-pass transmembrane protein insertion into ER membrane. Located in mitochondrion. Part of multi-pass translocon complex. Implicated in craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 2. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20831 | RAB5IF Knockout cell line (HeLa) | Human | RAB5IF | 1:3~1:6 | Negative | Online Inquiry |
KO20832 | RAB5IF Knockout cell line (HCT 116) | Human | RAB5IF | 1:2~1:4 | Negative | Online Inquiry |
KO20833 | RAB5IF Knockout cell line (HEK293) | Human | RAB5IF | 1:3~1:6 | Negative | Online Inquiry |
KO20834 | RAB5IF Knockout cell line (A549) | Human | RAB5IF | 1:3~1:4 | Negative | Online Inquiry |
RAB5IF Gene Knockout Cell Lines represent a cutting-edge biological product designed for advanced cellular research focused on the RAB5IF gene, a crucial player in intracellular trafficking and membrane dynamics. These cell lines are engineered to have a complete deletion of the RAB5IF gene, allowing researchers to examine the physiological roles and molecular mechanisms associated with RAB5IF independently from its native functional context.
The primary function of RAB5IF involves its participation in the regulation of early endosome dynamics and fusion processes, acting as a molecular switch in endocytic pathways. By utilizing these knockout cell lines, researchers can analyze the downstream effects of RAB5IF absence on cellular signaling, endosome biogenesis, and overall cell viability. The gene knockout model serves as a powerful tool in elucidating the contributions of RAB5IF to disease states, particularly in cancer and neurodegenerative disorders, where aberrations in endocytosis are often implicated.
From a scientific standpoint, these cell lines equip researchers with an invaluable resource for assessing the impact of RAB5IF on various biological processes, effectively aiding in drug development and therapeutic strategies. The availability of RAB5IF knockout cell lines accelerates the investigation of gene function in a controlled environment, facilitating breakthroughs in understanding disease mechanisms and potential interventions.
What sets our RAB5IF Gene Knockout Cell Lines apart from traditional methods is the precision with which the knockout is achieved—compared to alternative strategies like RNA interference, which may lead to partial knockdown rather than complete abrogation of gene function. This specificity affords researchers greater confidence in their findings, leading to reduced complexities in data interpretation.
In summary, RAB5IF Gene Knockout Cell Lines are an essential addition to the toolkit of researchers and clinicians engaged in the exploration of intracellular dynamics and their implications in health and disease. With a commitment to advancing scientific knowledge, our company specializes in providing high-quality biological products tailored to meet the rigorous demands of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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