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RAB42 Knockout Cell Lines

Gene: RAB42

Official Full Name: RAB42, member RAS oncogene familyprovided by HGNC

Gene Summary: Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30629 RAB42 Knockout cell line (HeLa) Human RAB42 1:3~1:6 Negative Online Inquiry
KO30630 RAB42 Knockout cell line (A549) Human RAB42 1:3~1:4 Negative Online Inquiry

Background

RAB42 Gene Knockout Cell Lines are genetically engineered cell models designed specifically to investigate the biological role of the RAB42 gene, a member of the RAB GTPase family known to be involved in intracellular trafficking processes. By employing CRISPR-Cas9 technology, these cell lines exhibit a complete knockout of the RAB42 gene, enabling researchers to study the gene’s function and its implications in various cellular pathways and diseases.

The primary mechanism of action hinges on the loss of RAB42, which is believed to play a critical role in vesicle transport and membrane dynamics. By disrupting its expression, researchers can observe the resultant phenotypes and molecular changes, shedding light on RAB42’s involvement in cellular homeostasis, endocytosis, and exocytosis. This comprehensive understanding may reveal how dysregulation of RAB42 contributes to disease states such as cancer or neurodegenerative disorders.

The scientific importance of RAB42 Gene Knockout Cell Lines is underscored by their applicability in both basic research and clinical studies. They provide invaluable insights into fundamental cellular processes and can serve as models for drug screening or the development of targeted therapies. Their use in translational research could lead to breakthroughs in therapeutic strategies for RAB42-related pathologies.

Compared to alternative models, RAB42 Gene Knockout Cell Lines offer a streamlined, reliable, and versatile solution for exploring the specific functions of RAB42. Traditional methods, such as knockdown techniques, may not achieve complete gene disruption, potentially leading to confounding results. Our cell lines guarantee a complete loss of function, ensuring that researchers can confidently attribute observed effects specifically to the absence of RAB42.

For researchers and clinicians looking to deepen their understanding of intracellular transport mechanisms and their relation to various diseases, our RAB42 Gene Knockout Cell Lines represent a crucial tool that can enhance experimental accuracy and efficacy. Our company is committed to providing high-quality biological products and robust support, backed by extensive expertise in genetic engineering and cellular biology, to ensure that you achieve your research goals effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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