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RAB3B Knockout Cell Lines

Gene: RAB3B

Official Full Name: RAB3B, member RAS oncogene familyprovided by HGNC

Gene Summary: Enables GDP binding activity; GTPase activity; and myosin V binding activity. Involved in several processes, including positive regulation of dopamine uptake involved in synaptic transmission; regulation of synaptic vesicle cycle; and regulation of vesicle size. Located in perinuclear region of cytoplasm and vesicle. Is active in dopaminergic synapse and synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35724 RAB3B Knockout cell line (HeLa) Human RAB3B 1:3~1:6 Negative Online Inquiry
KO35725 RAB3B Knockout cell line (HCT 116) Human RAB3B 1:2~1:4 Negative Online Inquiry
KO35726 RAB3B Knockout cell line (HEK293) Human RAB3B 1:3~1:6 Negative Online Inquiry
KO35727 RAB3B Knockout cell line (A549) Human RAB3B 1:3~1:4 Negative Online Inquiry

Background

RAB3B Gene Knockout Cell Lines are sophisticated biological tools engineered to provide researchers with the ability to study the functions and mechanisms of the RAB3B gene, a key player in intracellular vesicle trafficking and neurotransmitter release. Utilizing the CRISPR-Cas9 gene-editing technology, these cell lines are precisely modified to disable the RAB3B gene, allowing for in-depth examination of its role in cellular processes and its implications in various diseases such as neurological disorders, cancer, and metabolic syndromes.

These knockout cell lines function by disrupting the normal expression of RAB3B, providing a controlled environment to analyze changes in cellular behavior, signaling pathways, and gene expression profiles. This mechanism enables researchers to unveil the physiological and pathological roles of RAB3B in both in vitro and in vivo models, thereby enriching our understanding of its contributions to cellular dynamics and disease states.

The scientific importance of RAB3B Gene Knockout Cell Lines is manifold, offering valuable insights in both basic and applied research. Clinically, they serve as critical platforms for drug discovery and testing, contributing to the development of targeted therapies that mitigate the effects of diseases associated with dysfunctional RAB3B signaling.

What sets these knockout cell lines apart from commercially available alternatives is their high specificity, reliability, and validation. Each line undergoes rigorous testing to ensure complete knockout of the target gene without off-target effects, thus providing reproducible and consistent results. Moreover, the versatile applications range from neurobiology studies to cancer research, making them indispensable assets for a wide array of scientific inquiries.

For researchers and clinicians dedicated to advancing the frontiers of cellular and molecular biology, RAB3B Gene Knockout Cell Lines offer an unparalleled opportunity to dissect the complexities of gene function and to explore innovative therapeutic avenues. Backed by our company’s expertise in gene editing technology and commitment to quality, these products stand at the forefront of biological research and medical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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