Gene: RAB39A
Official Full Name: RAB39A, member RAS oncogene familyprovided by HGNC
Gene Summary: Predicted to enable GTP binding activity and GTPase activity. Involved in phagosome acidification and phagosome-lysosome fusion. Located in phagocytic vesicle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14746 | RAB39A Knockout cell line (HEK293) | Human | RAB39A | 1:3~1:6 | Negative | Online Inquiry |
RAB39A Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to deactivate the RAB39A gene, which plays a critical role in various cellular processes including endosomal trafficking and the regulation of intracellular signaling pathways. By utilizing CRISPR-Cas9 gene editing technology, these cell lines provide researchers with a powerful tool to elucidate the functional implications of RAB39A in both physiological and pathological contexts.
The key function of these knockout cell lines lies in their ability to serve as a model for studying the absence of RAB39A and its subsequent effects on cellular metabolism, neurogenesis, and cellular response to stressors. The disruption of this gene can significantly impact vesicle transport mechanisms, which are crucial for maintaining cellular homeostasis. By observing alterations in phenotype and cellular signaling in the context of RAB39A knockout, researchers can uncover valuable insights into related diseases, including neurodegenerative disorders, where RAB proteins have shown potential involvement.
From a scientific perspective, RAB39A Gene Knockout Cell Lines are indispensable in advancing both basic and translational research. These cell lines allow for the examination of gene function and protein interaction studies, and they can facilitate drug screening processes that target pathways influenced by RAB39A. Their application in disease models can also provide a better understanding of the pathophysiology underlying various health issues, thus paving the way for novel therapeutic strategies.
Compared to traditional methods of gene manipulation, RAB39A Gene Knockout Cell Lines offer specific advantages such as the precision brought by CRISPR technology, high efficiency in gene disruption, and consistency across experiments owing to standardized cell line applications. This leads to more reproducible data and enhances the reliability of research findings.
For researchers and clinicians focused on understanding cellular processes regulated by RAB39A, employing these specialized knockout cell lines is invaluable. They not only streamline experimental workflows but also ultimately contribute to the discovery of breakthroughs in neurobiology and other fields.
At our company, we are dedicated to providing high-quality biological products that empower the scientific community, and our RAB39A Gene Knockout Cell Lines are a testament to our expertise and commitment to advancing human health through innovative research solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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