Gene: RAB36
Official Full Name: RAB36, member RAS oncogene familyprovided by HGNC
Gene Summary: Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in vesicle-mediated transport. Predicted to be located in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33040 | RAB36 Knockout cell line (HCT 116) | Human | RAB36 | 1:2~1:4 | Negative | Online Inquiry |
KO33041 | RAB36 Knockout cell line (HEK293) | Human | RAB36 | 1:3~1:6 | Negative | Online Inquiry |
KO33042 | RAB36 Knockout cell line (A549) | Human | RAB36 | 1:3~1:4 | Negative | Online Inquiry |
RAB36 Gene Knockout Cell Lines are genetically engineered cells in which the RAB36 gene has been selectively inactivated, enabling researchers to explore the functional roles of this gene in cellular processes. The RAB36 gene encodes a member of the RAB family of small GTPases, which are pivotal in the regulation of intracellular trafficking, particularly in exocytosis and endocytic pathways. By utilizing CRISPR/Cas9 technology, these knockout cell lines provide a robust model for studying the downstream effects of RAB36 deficiency on various cellular mechanisms and signaling pathways.
The primary function of RAB36 involves the modulation of membrane traffic, and its disruption can lead to alterations in cellular homeostasis, potentially influencing processes such as secretion and vesicle transport. This alteration allows researchers to investigate the molecular pathways that are dependent on RAB36 activity and its implications in conditions like cancer, neurodegenerative diseases, and metabolic disorders.
In both research and clinical applications, RAB36 Gene Knockout Cell Lines serve as invaluable tools for elucidating the biological significance of RAB36. They enable high-throughput screening, drug discovery, and fundamental research into genetic factors that contribute to disease pathogenesis. Compared to traditional wild-type cell lines, knockout lines offer a powerful approach to understanding gene functions in a more context-specific manner.
One of the distinctive advantages of RAB36 knockout cell lines is their ability to provide clear insights into the specific role of RAB36 without the confounding influence of normal gene function. This specificity is crucial for developing targeted therapies and biomarkers. Furthermore, researchers benefit from robust phenotypic data that can guide therapeutic strategies aimed at modulating RAB36 pathways.
Our company specializes in advanced genetic engineering solutions, and our expertise in developing reliable, reproducible RAB36 Gene Knockout Cell Lines underscores our commitment to empowering researchers and clinicians in their quest for scientific knowledge and therapeutic advancements. By utilizing our product, you are not only gaining access to cutting-edge technology but also contributing to a deeper understanding of cellular dynamics that may pave the way for novel therapeutic interventions.
Please note that all services are for research use only. Not intended for any clinical use.
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