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RAB32 Knockout Cell Lines

Gene: RAB32

Official Full Name: RAB32, member RAS oncogene familyprovided by HGNC

Gene Summary: The protein encoded by this gene anchors the type II regulatory subunit of protein kinase A to the mitochondrion and aids in mitochondrial fission. The encoded protein also appears to be involved in autophagy and melanosome secretion. Variations in this gene may be linked to leprosy. [provided by RefSeq, Dec 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31353 RAB32 Knockout cell line (HeLa) Human RAB32 1:3~1:6 Negative Online Inquiry
KO31354 RAB32 Knockout cell line (HEK293) Human RAB32 1:3~1:6 Negative Online Inquiry
KO31355 RAB32 Knockout cell line (A549) Human RAB32 1:3~1:4 Negative Online Inquiry

Background

RAB32 Gene Knockout Cell Lines are a specialized tool designed for researchers aiming to investigate the cellular functions and pathways regulated by the RAB32 gene, known to be involved in intracellular trafficking and mitochondrial dynamics. These cell lines have been genetically engineered to achieve a complete knockout of the RAB32 gene, thereby facilitating the exploration of its biological roles in both normal and pathological conditions, such as cancer and neurodegenerative diseases.

The key mechanism behind the utility of RAB32 Gene Knockout Cell Lines lies in their ability to elucidate the molecular functions of RAB32 by comparing the knockout model with wild-type controls. By removing RAB32, researchers can observe alterations in cellular processes such as autophagy, vesicle trafficking, and mitochondrial function, providing essential insights into the gene's contribution to cellular homeostasis. These models are invaluable in uncovering novel therapeutic targets and understanding disease mechanisms that may arise from dysregulation of RAB32.

Scientifically, the importance of RAB32 Gene Knockout Cell Lines is underscored by their diverse applications in both research and clinical settings. They can be employed in drug discovery workflows to assess the potential impact of therapeutic compounds on disrupted cellular pathways linked to RAB32. Additionally, these cell lines serve as a critical asset in functional genomics studies, expanding our knowledge of gene-gene interactions and the signaling networks involved in cell behavior.

One of the standout advantages of RAB32 Gene Knockout Cell Lines compared to alternative models is their precise gene targeting, which ensures a clean knockout free from off-target effects often seen with other gene-editing technologies. This specificity enables researchers to draw more accurate conclusions from their experiments, ultimately leading to more reproducible results.

For researchers and clinicians, the value of RAB32 Gene Knockout Cell Lines extends beyond just a research tool; they represent a gateway to novel biological insights and potential therapeutic strategies aimed at diseases associated with mitochondrial dysfunction and cellular trafficking anomalies. Our company has a robust background in providing high-quality genetic models tailored to meet the evolving needs of the scientific community, ensuring that our customers have access to the latest advancements in molecular biology and genetics.

Please note that all services are for research use only. Not intended for any clinical use.

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