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RAB2B Knockout Cell Lines

Gene: RAB2B

Official Full Name: RAB2B, member RAS oncogene familyprovided by HGNC

Gene Summary: Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved in GTP binding and hydrolysis. Rab proteins are prenylated, membrane-bound proteins involved in vesicular fusion and trafficking; see MIM 179508.[supplied by OMIM, Apr 2006]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24453 RAB2B Knockout cell line (HeLa) Human RAB2B 1:3~1:6 Negative Online Inquiry
KO24454 RAB2B Knockout cell line (HCT 116) Human RAB2B 1:2~1:4 Negative Online Inquiry
KO24455 RAB2B Knockout cell line (HEK293) Human RAB2B 1:3~1:6 Negative Online Inquiry
KO24456 RAB2B Knockout cell line (A549) Human RAB2B 1:3~1:4 Negative Online Inquiry

Background

RAB2B Gene Knockout Cell Lines are genetically engineered cell lines where the RAB2B gene has been specifically inactivated, providing a vital tool for researchers investigating the roles of this gene in cellular processes and disease mechanisms. RAB2B, a member of the RAS oncogene family, plays a crucial role in vesicular transport and intracellular trafficking, influencing the secretion of proteins, membrane dynamics, and signal transduction pathways.

The key functionality of RAB2B Gene Knockout Cell Lines is their ability to allow scientists to observe the downstream effects of RAB2B loss-of-function in a controlled environment. By utilizing CRISPR-Cas9 gene editing technology, these cell lines exhibit a complete disruption of the RAB2B protein, thereby serving as a powerful model to elucidate its biological functions, particularly in relation to cancer biology and neurodegenerative diseases.

The significance of these knockout cell lines extends beyond basic research; they hold key implications for translational medicine. Understanding RAB2B's role in cellular mechanisms can lead to the identification of novel therapeutic targets, enhancing drug development strategies aimed at diseases where RAB2B is implicated. Such applications are invaluable in both academic and pharmaceutical research settings, providing insights that guide experimental designs and clinical approaches.

Compared to other gene knockout models, RAB2B Gene Knockout Cell Lines offer a unique combination of specificity and reproducibility, enhancing their utility in exploratory and confirmatory studies. Their establishment in varied cellular backgrounds also allows for versatile experimentation, enabling researchers to seamlessly integrate them into existing workflows.

For researchers and clinicians engaged in molecular biology and translational research, the availability of RAB2B Gene Knockout Cell Lines translates to accelerated research timelines and enhanced experimental outcomes. The precision of this cutting-edge product underscores its value and potential for pioneering discoveries in genetic regulation and cellular dynamics.

Our company is committed to providing high-quality, validated genetic tools that empower researchers to unlock the complexities of biological processes. Our expertise in genetic engineering and commitment to scientific advancement ensures that products like RAB2B Gene Knockout Cell Lines meet the rigorous standards needed to support innovative research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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