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RAB2A Knockout Cell Lines

Gene: RAB2A

Official Full Name: RAB2A, member RAS oncogene familyprovided by HGNC

Gene Summary: The protein encoded by this gene belongs to the Rab family, members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis. The Rabs are membrane-bound proteins, involved in vesicular fusion and trafficking. This protein is a resident of pre-Golgi intermediates, and is required for protein transport from the endoplasmic reticulum (ER) to the Golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07417 RAB2A Knockout cell line (HeLa) Human RAB2A 1:3~1:6 Negative Online Inquiry
KO07418 RAB2A Knockout cell line (HCT 116) Human RAB2A 1:2~1:4 Negative Online Inquiry
KO07419 RAB2A Knockout cell line (HEK293) Human RAB2A 1:3~1:6 Negative Online Inquiry
KO07420 RAB2A Knockout cell line (A549) Human RAB2A 1:3~1:4 Negative Online Inquiry

Background

RAB2A Gene Knockout Cell Lines are genetically engineered cell models specifically developed for the investigation of the RAB2A gene's functions and its role in various cellular processes. These cell lines are created through state-of-the-art CRISPR-Cas9 gene editing technology, which allows for precise deletion of the RAB2A gene. This targeted knockout facilitates in-depth studies of RAB2A's involvement in intracellular transport, vesicle trafficking, and cellular signaling pathways.

The primary function of RAB2A involves regulating the transport of proteins and lipids within cells, contributing significantly to the maintenance of cellular homeostasis. By utilizing RAB2A Knockout Cell Lines, researchers can elucidate the molecular mechanisms underlying these processes and assess the gene's implications in diseases such as cancer, neurodegeneration, and metabolic disorders. This is particularly valuable in clinical and translational research, where understanding the dysregulation of key genes can lead to novel therapeutic strategies.

Compared to traditional cell lines, the RAB2A Gene Knockout Cell Lines offer unique advantages, including higher specificity in targeting RAB2A functions and reduced off-target effects associated with other gene manipulation techniques. Moreover, the robustness of the knockout allows for clearer interpretation of experimental results, providing a more accurate representation of RAB2A's cellular roles.

For researchers and clinicians alike, the ability to investigate the gene’s intricate functions paves the way for the identification of potential biomarkers for diseases and the development of targeted treatments. The creation of these cell lines exemplifies our commitment to advancing scientific research and precision medicine.

Our company specializes in providing high-quality genetic tools for biomedical research, driven by a team of experts dedicated to fostering innovation in molecular biology applications. With our RAB2A Gene Knockout Cell Lines, we aim to empower researchers to unravel the complexities of gene function and disease mechanisms.

Please note that all services are for research use only. Not intended for any clinical use.

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