Gene: RAB29
Official Full Name: RAB29, member RAS oncogene familyprovided by HGNC
Gene Summary: Enables several functions, including dynein complex binding activity; guanyl ribonucleotide binding activity; and kinesin binding activity. Involved in several processes, including positive regulation of T cell receptor signaling pathway; positive regulation of receptor recycling; and retrograde transport, endosome to Golgi. Located in several cellular components, including Golgi apparatus; endosome; and vacuole. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO33710 | RAB29 Knockout cell line (HeLa) | Human | RAB29 | 1:3~1:6 | Negative | Online Inquiry |
KO33711 | RAB29 Knockout cell line (HCT 116) | Human | RAB29 | 1:2~1:4 | Negative | Online Inquiry |
KO33712 | RAB29 Knockout cell line (HEK293) | Human | RAB29 | 1:3~1:6 | Negative | Online Inquiry |
KO33713 | RAB29 Knockout cell line (A549) | Human | RAB29 | 1:3~1:4 | Negative | Online Inquiry |
RAB29 Gene Knockout Cell Lines are a valuable tool in the realm of genetic studies and cellular biology, specifically designed to facilitate the exploration of the RAB29 gene's functions through genetic disruption. These cell lines are engineered to possess a targeted knockout of the RAB29 gene, rendering it non-functional. This gene is known to play a significant role in vesicular trafficking within cells, particularly in processes related to endosomal and lysosomal function, making it crucial for various cellular homeostasis mechanisms.
The primary function of RAB29 is related to its GTPase activity, which regulates the transport of intracellular vesicles. By investigating these knockout cell lines, researchers can delineate the pathways influenced by RAB29, offering insights into its contributions to neurodegenerative diseases, autophagy, and intracellular signaling. These models allow for the study of phenotypic changes that occur in the absence of functional RAB29, thereby elucidating its role in both normal physiology and pathological conditions.
Scientifically, RAB29 Gene Knockout Cell Lines are essential for advancing research into gene function and the molecular mechanisms underlying disease. In clinical applications, they enable the evaluation of potential therapeutic targets and drug responses, providing a platform for translational research that bridges the gap from bench to bedside. Their precise targeting offers enhanced specificity compared to conventional siRNA approaches, which can result in off-target effects.
What sets RAB29 Gene Knockout Cell Lines apart from alternative products is their robust design, which ensures high efficiency in gene disruption and reproducibility in experimental outcomes. This specificity maximizes the reliability of research findings, making it a preferred choice for institutions focused on genetic and biopharmaceutical research.
For researchers and clinicians keen on unlocking the mysteries of cellular function and disease mechanisms, these cell lines present indispensable models for innovative investigations and therapeutic advancements. With a commitment to quality and scientific rigor, our company specializes in providing expert engineered cell lines tailored to facilitate groundbreaking research, ensuring you have the cutting-edge resources necessary to drive your studies forward.
Please note that all services are for research use only. Not intended for any clinical use.
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