Gene: RAB26
Official Full Name: RAB26, member RAS oncogene familyprovided by HGNC
Gene Summary: Members of the RAB protein family, including RAB26, are important regulators of vesicular fusion and trafficking. The RAB family of small G proteins regulates intercellular vesicle trafficking, including exocytosis, endocytosis, and recycling (summary by Seki et al., 2000 [PubMed 11043516]).[supplied by OMIM, Nov 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28716 | RAB26 Knockout cell line (HeLa) | Human | RAB26 | 1:3~1:6 | Negative | Online Inquiry |
KO28717 | RAB26 Knockout cell line (HCT 116) | Human | RAB26 | 1:2~1:4 | Negative | Online Inquiry |
KO28718 | RAB26 Knockout cell line (HEK293) | Human | RAB26 | 1:3~1:6 | Negative | Online Inquiry |
KO28719 | RAB26 Knockout cell line (A549) | Human | RAB26 | 1:3~1:4 | Negative | Online Inquiry |
RAB26 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the RAB26 gene's role in cellular processes. RAB26, a member of the RAB family of small GTPases, is known to be involved in intracellular transport and vesicle trafficking, crucial for maintaining cellular homeostasis and facilitating communication between organelles. By employing CRISPR/Cas9 technology or similar gene-editing methods, these knockout cell lines serve as valuable tools for researchers aiming to dissect the functions of RAB26 in various biological contexts.
The key functionality of RAB26 Gene Knockout Cell Lines lies in their ability to mimic loss-of-function conditions, allowing scientists to observe phenotypic changes and underlying molecular mechanisms when the gene is inactivated. This can lead to insights into RAB26's contributions to diseases related to vesicular transport dysfunction, such as neurodegenerative disorders and cancer. Furthermore, these cell lines can be utilized in drug screening assays to evaluate potential therapeutics targeting the pathways regulated by RAB26.
The scientific importance of RAB26 Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical settings. They provide a robust model for elucidating gene function, studying signaling pathways, and exploring therapeutic interventions in diseases where RAB26 is implicated. Additionally, these cell lines are invaluable in validating genetic targets and may serve as a platform for the development of gene therapies.
Compared to alternative models such as wild-type cell lines or knockout animal models, RAB26 Gene Knockout Cell Lines offer greater specificity and ease of use. Researchers benefit from reduced variability in background gene expression, making it easier to delineate the effects of RAB26 in studies.
For researchers and clinicians seeking to unlock new paradigms in cell biology or therapeutic development, the RAB26 Gene Knockout Cell Lines represent an essential resource. By providing tools that enable precise manipulation of gene functions, these products empower scientific innovation.
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Please note that all services are for research use only. Not intended for any clinical use.
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