Home / RAB21 Knockout Cell Lines

RAB21 Knockout Cell Lines

Gene: RAB21

Official Full Name: RAB21, member RAS oncogene familyprovided by HGNC

Gene Summary: This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30022 RAB21 Knockout cell line (HeLa) Human RAB21 1:3~1:6 Negative Online Inquiry
KO30023 RAB21 Knockout cell line (HCT 116) Human RAB21 1:2~1:4 Negative Online Inquiry
KO30024 RAB21 Knockout cell line (HEK293) Human RAB21 1:3~1:6 Negative Online Inquiry
KO30025 RAB21 Knockout cell line (A549) Human RAB21 1:3~1:4 Negative Online Inquiry

Background

RAB21 Gene Knockout Cell Lines are specifically engineered cellular models designed to elucidate the functions of the RAB21 gene, a member of the RAS oncogene family known to play significant roles in intracellular vesicle transport and membrane trafficking. These cell lines enable researchers to investigate the downstream effects of RAB21 gene disruption, providing insights into its contribution to various cellular processes such as endocytosis and exocytosis. Through CRISPR/Cas9 technology, RAB21 knockout cells have been generated, resulting in a complete absence of RAB21 protein expression, facilitating a deeper understanding of its biological relevance.

The primary function of these cell lines lies in their ability to model specific biological pathways impacted by RAB21, enabling researchers to explore its implications in normal cellular physiology and pathophysiological conditions, such as cancer metastasis and neurodegenerative diseases. The unique mechanism of action allows scientists to dissect the molecular interactions and identify potential therapeutic targets influenced by the absence of RAB21.

Scientifically, RAB21 Gene Knockout Cell Lines represent a significant advancement in the field of molecular biology and genetics. Their applications extend to drug discovery, toxicology testing, and comprehensive studies in gene function, making them essential tools in both academic research and clinical investigations.

What sets RAB21 Gene Knockout Cell Lines apart from alternative models is their precision engineering and adaptability to various experimental environments. Researchers benefit from their consistent performance and reproducibility, crucial for obtaining reliable and meaningful results. These knockout lines are also compatible with a wide range of applications, including high-throughput screening and pathway analysis, further enhancing their utility.

For researchers and clinicians aiming to uncover the complexities of cellular mechanisms or develop novel therapeutic strategies, RAB21 Gene Knockout Cell Lines provide immense value. Their ability to mimic human disease conditions offers a more relevant context for identifying promising interventions.

With years of expertise in cellular and molecular biology, our company is committed to providing high-quality biological products, including RAB21 Gene Knockout Cell Lines, to advance scientific discovery and support healthcare innovations.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.