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QPCT Knockout Cell Lines

Gene: QPCT

Official Full Name: glutaminyl-peptide cyclotransferaseprovided by HGNC

Gene Summary: This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28821 QPCT Knockout cell line (HEK293) Human QPCT 1:3~1:6 Negative Online Inquiry
KO28822 QPCT Knockout cell line (A549) Human QPCT 1:3~1:4 Negative Online Inquiry

Background

QPCT Gene Knockout Cell Lines are specialized models designed for the precise study of the Quinone-Containing Protein Transporters (QPCT) gene functions in human and mammalian biology. These cell lines are generated through advanced gene-editing technologies such as CRISPR/Cas9, leading to the effective knockout of the QPCT gene, which plays a critical role in cellular processes including detoxification and metabolic regulation.

The primary functionality of QPCT Gene Knockout Cell Lines lies in their ability to provide researchers with a controlled environment to dissect the molecular pathways affected by QPCT loss. Through the assessment of phenotypic changes in these knockout models, scientists can elucidate specific pathways involved in drug metabolism, environmental toxin response, and various disease mechanisms. These cell lines serve as valuable tools in functional genomics, pharmacology, and toxicology, allowing researchers to identify gene functions and interactions that are otherwise challenging to observe in vivo.

From a scientific perspective, the applications of QPCT knockout cell lines extend into drug discovery, where they can be utilized to screen new therapeutics for targeting metabolic pathways disrupted by the absence of QPCT. They also provide insights into diseases related to metabolic dysfunction, thereby enhancing understanding in clinical research settings.

A unique selling proposition of our QPCT Gene Knockout Cell Lines is their rigorous validation and reliability, ensuring that researchers can trust the consistency and reproducibility of their experimental results. Additionally, these cell lines are accompanied by comprehensive technical support and guidance on experimental design, unlike many alternatives which may lack substantiated documentation.

By choosing our QPCT Gene Knockout Cell Lines, researchers and clinicians gain access to a robust platform that accelerates their investigations into gene function and the development of therapeutic strategies. Our commitment to scientific excellence and innovation positions us as a leader in providing high-quality biological products tailored for advanced biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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