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QKI Knockout Cell Lines

Gene: QKI

Official Full Name: QKI, KH domain containing RNA bindingprovided by HGNC

Gene Summary: The protein encoded by this gene is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. The encoded protein is involved in myelinization and oligodendrocyte differentiation and may play a role in schizophrenia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01043 QKI Knockout cell line (HeLa) Human QKI 1:3~1:6 Negative Online Inquiry
KO33225 QKI Knockout cell line (HCT 116) Human QKI 1:2~1:4 Negative Online Inquiry
KO33226 QKI Knockout cell line (HEK293) Human QKI 1:3~1:6 Negative Online Inquiry
KO33227 QKI Knockout cell line (A549) Human QKI 1:3~1:4 Negative Online Inquiry

Background

QKI Gene Knockout Cell Lines are genetically engineered cell lines that have had the QKI (Quaking, KH-type splicing regulatory protein) gene inactivated, enabling researchers to elucidate the role of this critical gene in various biological processes. QKI is known for its involvement in RNA splicing and regulation, as well as its impact on myelination in the central nervous system. By creating these knockout cell lines, researchers gain invaluable tools to investigate the consequences of QKI loss, advancing our understanding of developmental biology, neurobiology, and associated pathologies.

The key function of QKI Gene Knockout Cell Lines lies in their ability to serve as models for studying gene function and cellular responses in a controlled environment. By selectively disabling the QKI gene, researchers can observe changes in cellular behavior, gene expression, and RNA processing, providing insights into its mechanisms of action. These insights may contribute to unraveling complex disease mechanisms, particularly in neurological disorders and cancers where QKI has been implicated.

Scientifically, the development of QKI Gene Knockout Cell Lines represents a significant advancement in molecular biology research. They find ample applications in various fields, from drug discovery to gene therapy, and are particularly valuable in elucidating the roles of splicing factors and their associated pathways. Their use in comparative studies against wild-type cell lines offers researchers an experimental advantage to investigate gene regulatory networks.

What sets QKI Gene Knockout Cell Lines apart from traditional cell lines is their specificity and precision in gene manipulation, which provides clearer and more reproducible results. With a focus on enhancing targeted research capabilities, these cell lines eliminate the confounding effects that often accompany incomplete gene knockout strategies. Researchers can have confidence in their results, leading to more accurate conclusions and innovations.

Investing in QKI Gene Knockout Cell Lines empowers researchers and clinicians to push the boundaries of our understanding of gene functionality. By utilizing these advanced models, they can contribute to the development of targeted therapies and interventions for genetic disorders and diseases linked to QKI dysregulation.

Our company prides itself on its expertise in developing high-quality biological products like QKI Gene Knockout Cell Lines. We are committed to providing researchers with superior tools necessary to advance scientific knowledge and innovation in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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