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PUDP Knockout Cell Lines

Gene: PUDP

Official Full Name: pseudouridine 5'-phosphataseprovided by HGNC

Gene Summary: This gene encodes a member of the haloacid dehalogenase-like (HAD) hydrolase superfamily. The encoded protein has no known biological function. This gene has a pseudogene on chromosome 1. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34289 PUDP Knockout cell line (HeLa) Human PUDP 1:3~1:6 Negative Online Inquiry
KO34290 PUDP Knockout cell line (HCT 116) Human PUDP 1:2~1:4 Negative Online Inquiry
KO34291 PUDP Knockout cell line (HEK293) Human PUDP 1:3~1:6 Negative Online Inquiry
KO34292 PUDP Knockout cell line (A549) Human PUDP 1:3~1:4 Negative Online Inquiry

Background

PUDP Gene Knockout Cell Lines are sophisticated cellular models specifically engineered to facilitate the study of the PUDP gene's role in various biological processes. These cell lines have undergone targeted gene editing using cutting-edge CRISPR/Cas9 technology, resulting in the complete ablation of the PUDP gene. This alteration allows researchers to elucidate the functional pathways and molecular interactions that are influenced by PUDP, a gene implicated in crucial metabolic processes.

The key functions of these knockout cell lines revolve around their ability to mimic disease states or gene deficiencies relevant to numerous fields, including cancer research, drug metabolism, and gene function studies. By eliminating PUDP, researchers can assess the gene's role in nucleotide synthesis, cell proliferation, and other metabolic factors, using these lines as a platform to explore gene-gene interactions and the consequent phenotypic outcomes.

The scientific importance of PUDP Gene Knockout Cell Lines extends to their applications in both basic research and clinical settings. These models are instrumental for pharmacological studies aiming to understand drug responses and toxicology by simulating conditions that occur in human diseases, enhancing the relevance of experimental findings to human health.

In comparison to traditional cell lines or non-targeted methods, PUDP Gene Knockout Cell Lines offer unique advantages, including specificity and reproducibility. This precision allows researchers to generate results with greater confidence, reducing variability that often complicates interpretations in studies utilizing unedited cell lines.

For researchers, clinicians, and pharmaceutical companies dedicated to advancing their understanding of gene function and its implications on health and disease, PUDP Gene Knockout Cell Lines represent a powerful tool. They provide a clearer glimpse into the complexities of cellular mechanisms, ultimately contributing to the development of targeted therapies and personalized medicine strategies.

Our company excels in providing high-quality biological products and expert support, ensuring that you can seamlessly integrate these advanced cell lines into your research paradigm to propel your projects forward with precision and insight.

Please note that all services are for research use only. Not intended for any clinical use.

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