Gene: PTPRS
Official Full Name: protein tyrosine phosphatase receptor type Sprovided by HGNC
Gene Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04099 | PTPRS Knockout cell line (HeLa) | Human | PTPRS | 1:3~1:6 | Negative | Online Inquiry |
KO04100 | PTPRS Knockout cell line (HCT 116) | Human | PTPRS | 1:2~1:4 | Negative | Online Inquiry |
KO04101 | PTPRS Knockout cell line (HEK293) | Human | PTPRS | 1:3~1:6 | Negative | Online Inquiry |
KO04102 | PTPRS Knockout cell line (A549) | Human | PTPRS | 1:3~1:4 | Negative | Online Inquiry |
PTPRS Gene Knockout Cell Lines represent a groundbreaking tool in molecular biology that enables researchers to study the specific functions of the phosphatase and tensin homolog PTPRS gene. These cell lines are genetically modified to knock out the expression of the PTPRS gene, providing a unique platform for investigating the gene's role in cellular signaling pathways and disease mechanisms.
The primary function of PTPRS involves the regulation of extracellular signaling and the modulation of growth factor receptor activity. By utilizing these knockout cell lines, researchers can observe the consequential effects of PTPRS deletion on cellular behaviors, such as proliferation, differentiation, and apoptosis. The mechanisms underlying these changes become clearer, enabling more targeted investigations into various conditions, including cancer, diabetes, and neurodegenerative diseases.
From a scientific standpoint, PTPRS Gene Knockout Cell Lines are invaluable for both basic research and therapeutic development. In research settings, they facilitate functional assays that characterize the biological implications of PTPRS activity. In clinical contexts, understanding PTPRS functions may lead to novel therapeutic targets for diseases where this gene is implicated.
Compared to alternative models, such as wild-type cell lines or transiently transfected cells, PTPRS Gene Knockout Cell Lines provide more stable and reliable data. This stability ensures reproducibility in experiments, ultimately increasing the rigor and credibility of research findings. Furthermore, these cell lines allow for the exploration of gene interactions over extended periods, which is often not feasible with transient models.
For researchers and clinicians focused on the intricate world of cellular signaling and its implications for health and disease, PTPRS Gene Knockout Cell Lines offer a powerful ally. They enable the exploration of complex biological questions in an efficient and insightful manner. Our company, [Your Company Name], specializes in the production of high-quality genetic models, backed by years of experience in molecular biology and a commitment to advancing research capabilities. With a robust portfolio and unparalleled expertise, we are dedicated to supporting your scientific discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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