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PTN Knockout Cell Lines

Gene: PTN

Official Full Name: pleiotrophinprovided by HGNC

Gene Summary: The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35829 PTN Knockout cell line (HEK293) Human PTN 1:3~1:6 Negative Online Inquiry

Background

PTN Gene Knockout Cell Lines are specially engineered cellular systems that have been modified to lack the expression of the PTN gene, a crucial player in various biological processes including cellular growth, differentiation, and signaling. These cell lines serve as an invaluable tool for researchers aiming to elucidate the role of the PTN gene in health and disease. By knocking out the PTN gene, researchers can observe resultant phenotypic changes, thus gaining deeper insights into its functional significance and potential implications in pathological conditions.

The underlying mechanism involves targeted gene editing techniques, such as CRISPR-Cas9, which enables precise modifications at the genomic level. The resulting knockout phenotypes allow for the assessment of PTN's contribution to cellular behaviors, including proliferation rates, response to external stimuli, and interaction with other cellular pathways. This contributes to a more comprehensive understanding of the gene's role in developmental biology and disease mechanisms, making these cell lines essential for both basic and applied research.

In research and clinical contexts, understanding the implications of PTN gene alterations is pivotal, especially in the fields of oncology and regenerative medicine. Scientists can utilize these cell lines to investigate potential therapeutic targets and develop novel treatment strategies for diseases associated with PTN dysregulation. Furthermore, the inherent versatility of PTN Gene Knockout Cell Lines allows them to be utilized across various experimental setups, from drug screening to gene therapy development.

When compared to alternative models, such as animal systems or non-specific knockdown methods, PTN Gene Knockout Cell Lines offer enhanced precision and reproducibility. These cell lines provide a more controlled environment to study gene function, which significantly reduces variability and enhances the reliability of data generated. Additionally, the convenience of in vitro models allows for high-throughput screening and easier manipulation for downstream applications.

In summary, PTN Gene Knockout Cell Lines provide researchers and clinicians with a robust and precise approach to dissecting gene function and its relevance in disease. Our commitment to delivering high-quality, innovative biological products positions us as a leader in the field, ensuring that our customers have access to cutting-edge tools that drive scientific discovery forward.

Please note that all services are for research use only. Not intended for any clinical use.

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