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PTGR2 Knockout Cell Lines

Gene: PTGR2

Official Full Name: prostaglandin reductase 2provided by HGNC

Gene Summary: This gene encodes an enzyme involved in the metabolism of prostaglandins. The encoded protein catalyzes the NADPH-dependent conversion of 15-keto-prostaglandin E2 to 15-keto-13,14-dihydro-prostaglandin E2. This protein may also be involved in regulating activation of the peroxisome proliferator-activated receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24055 PTGR2 Knockout cell line (HeLa) Human PTGR2 1:3~1:6 Negative Online Inquiry
KO24056 PTGR2 Knockout cell line (HCT 116) Human PTGR2 1:2~1:4 Negative Online Inquiry
KO24057 PTGR2 Knockout cell line (HEK293) Human PTGR2 1:3~1:6 Negative Online Inquiry
KO24058 PTGR2 Knockout cell line (A549) Human PTGR2 1:3~1:4 Negative Online Inquiry

Background

PTGR2 Gene Knockout Cell Lines are advanced cellular models engineered to precisely disrupt the function of the PTGR2 gene, known to play a crucial role in various biological processes, including lipid metabolism and inflammatory responses. By utilizing CRISPR-Cas9 technology, these cell lines enable researchers to study the downstream effects of PTGR2 deficiency, thereby elucidating its specific contributions to disease mechanisms.

The primary function of PTGR2 Gene Knockout Cell Lines lies in their ability to provide insights into the gene's physiological and pathological roles. The knockout effectively eliminates any PTGR2 protein expression, allowing scientists to investigate alterations in metabolic pathways, cellular signaling, and gene expression profiles. This mechanism is particularly beneficial for understanding conditions like atherosclerosis, obesity, and other metabolic syndromes associated with abnormal lipid metabolism.

The scientific importance of these cell lines extends into both research and clinical applications. They serve as invaluable tools for drug discovery, allowing pharmaceutical companies to screen for potential therapeutics that target lipid-related disorders. Moreover, they contribute to our understanding of inflammation's impact on various diseases, which could enhance therapeutic strategies aimed at modulating immune responses.

Compared to traditional models, PTGR2 Gene Knockout Cell Lines offer a greater specificity and reliability in genetic analysis, reducing the confounding variables often present in earlier models. Their robust design ensures reproducibility in experiments, yielding high-quality data crucial for both exploratory and confirmatory studies.

For researchers and clinicians seeking to unravel the complexities of metabolic disorders, PTGR2 Gene Knockout Cell Lines represent an unparalleled resource that bridges laboratory findings with real-world medical applications. They empower users to make significant advances in understanding disease mechanisms, facilitating the development of targeted therapies.

With years of expertise in biotechnological innovation, our company is committed to providing top-tier genetic tools and biological products that enhance research capabilities and drive scientific progress. Our dedication to quality and precision ensures that you receive cell lines that meet the demanding standards of modern research.

Please note that all services are for research use only. Not intended for any clinical use.

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