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PTGR1 Knockout Cell Lines

Gene: PTGR1

Official Full Name: prostaglandin reductase 1provided by HGNC

Gene Summary: This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO05137 PTGR1 Knockout cell line (HeLa) Human PTGR1 1:3~1:6 Negative Online Inquiry
KO05138 PTGR1 Knockout cell line (HCT 116) Human PTGR1 1:2~1:4 Negative Online Inquiry
KO05139 PTGR1 Knockout cell line (HEK293) Human PTGR1 1:3~1:6 Negative Online Inquiry
KO05140 PTGR1 Knockout cell line (A549) Human PTGR1 1:3~1:4 Negative Online Inquiry

Background

PTGR1 Gene Knockout Cell Lines are a state-of-the-art biological product designed to facilitate research into the functions of the PTGR1 gene, which plays a pivotal role in the metabolic pathways of various cellular processes. These cell lines have been genetically engineered to have a targeted knockout of the PTGR1 gene, allowing researchers to overcome challenges associated with gene function analysis, signaling pathways, and disease modeling.

Using CRISPR-Cas9 technology, we have achieved precise and efficient knockout of the PTGR1 gene. This targeted approach leads to a clear phenotypic manifestation that enables researchers to study the gene’s role in cellular metabolism, oxidative stress responses, and implications in disease states such as cancer and metabolic disorders. The absence of PTGR1 allows for streamlined observation of compensatory mechanisms and can elucidate the gene’s contribution to pathological conditions.

The scientific importance of PTGR1 Gene Knockout Cell Lines extends into both research and clinical applications. In research settings, these lines serve as vital tools for drug discovery and the evaluation of metabolic pathways, while in clinical environments, they offer a means for developing potential therapeutic strategies by understanding the gene’s involvement in specific diseases.

What sets our PTGR1 Gene Knockout Cell Lines apart from alternative models is their validated performance and reliability. They are developed under stringent quality control conditions and backed by comprehensive user protocols, ensuring researchers can replicate experiments with confidence. Our product is specifically tailored to maximize the efficiency of experiments whilst reducing time and resources, empowering scientists to achieve significant breakthroughs.

Valuable to researchers and clinicians alike, PTGR1 Gene Knockout Cell Lines enable advanced studies that can lead to novel therapeutic targets and actionable insights into gene functions. At our company, we are committed to advancing scientific research by providing high-quality biological products backed by expert support and extensive experience in genetic engineering.

Please note that all services are for research use only. Not intended for any clinical use.

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