Gene: PSRC1
Official Full Name: proline and serine rich coiled-coil 1provided by HGNC
Gene Summary: This gene encodes a proline-rich protein that is a target for regulation by the tumor suppressor protein p53. The encoded protein plays an important role in mitosis by recruiting and regulating microtubule depolymerases that destabalize microtubules. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Apr 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24680 | PSRC1 Knockout cell line (HeLa) | Human | PSRC1 | 1:3~1:6 | Negative | Online Inquiry |
KO24681 | PSRC1 Knockout cell line (HCT 116) | Human | PSRC1 | 1:2~1:4 | Negative | Online Inquiry |
KO24682 | PSRC1 Knockout cell line (HEK293) | Human | PSRC1 | 1:3~1:6 | Negative | Online Inquiry |
KO24683 | PSRC1 Knockout cell line (A549) | Human | PSRC1 | 1:3~1:4 | Negative | Online Inquiry |
PSRC1 Gene Knockout Cell Lines are genetically engineered cellular models designed to specifically inactivate the PSRC1 gene, which encodes a protein implicated in various biological processes including cellular signaling, cell cycle regulation, and transcriptional control. These cell lines are invaluable tools for researchers focused on elucidating the role of PSRC1 in cellular function, disease mechanisms, and novel therapeutic approaches.
The primary function of PSRC1 Gene Knockout Cell Lines is to enable the investigation of the PSRC1 gene's contributions to biological pathways and its impact on cellular behavior under normal and pathological conditions. By utilizing CRISPR-Cas9 technology or alternative gene-editing techniques, these cell lines allow scientists to create a precise null phenotype, facilitating studies on how the absence of PSRC1 affects cellular processes such as proliferation, apoptosis, and response to stressors.
In terms of scientific importance, PSRC1 has been associated with tumorigenesis and various forms of cancer, making these knockout cell lines particularly relevant for cancer research. They serve as excellent platforms for drug screening, gene function studies, and exploring potential genetic interactions that could reveal novel therapeutic targets. Furthermore, they can be used in the development of gene therapies and personalized medicine approaches.
The unique selling points of PSRC1 Gene Knockout Cell Lines include their specificity and reliability compared to traditional methods of gene knockdown, such as RNA interference, which may lead to incomplete or off-target effects. These knockout lines provide a more definitive model for studying gene function, making them more suitable for high-impact research.
For researchers, clinicians, and biotechnologists, utilizing PSRC1 Gene Knockout Cell Lines enhances the understanding of PSRC1's role in cellular regulation and disease progression, ultimately leading to informed approaches in therapeutic development. Our company specializes in the generation of high-quality genetic models and is committed to advancing research capabilities with our extensive portfolio, ensuring that scientists have access to the most precise and robust tools available.
Please note that all services are for research use only. Not intended for any clinical use.
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