Gene: PSG4
Official Full Name: pregnancy specific beta-1-glycoprotein 4provided by HGNC
Gene Summary: The protein encoded by this gene is a pregnancy-specific glycoprotein (PSG), one of several encoded by a cluster of similar genes on chromosome 19. This gene is a member of the carcinoembryonic antigen (CEA) gene family and may play a role in regulation of the innate immune system. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35860 | PSG4 Knockout cell line (A549) | Human | PSG4 | 1:3~1:4 | Negative | Online Inquiry |
PSG4 Gene Knockout Cell Lines are genetically modified cellular models designed to investigate the physiological and pathological roles of the PSG4 gene, which is associated with various biological processes including immunomodulation and fetal development. These knockout cell lines are engineered to have complete ablation of the PSG4 gene, allowing researchers to explore its function and significance in cellular context by comparing these cells to their wild-type counterparts.
The primary function of PSG4 Gene Knockout Cell Lines lies in their ability to provide insights into gene expression profiles, cellular behavior, and signaling pathways regulated by PSG4. By observing the phenotypic and molecular changes that occur in the absence of this gene, researchers can decipher the complex biological roles played by PSG4 in immune responses, pregnancy, and potential pathologies such as preeclampsia or other gestational-related conditions.
These cell lines possess significant scientific importance, serving as a powerful tool for both basic research and translational applications. In a laboratory setting, PSG4 knockout models can facilitate enhanced understanding of the mechanisms involved in immune tolerance during pregnancy and contribute to the development of targeted therapies for pregnancy-related complications or autoimmune disorders.
Key advantages of PSG4 Gene Knockout Cell Lines over traditional models include their precise genetic modifications, which eliminate off-target effects often seen in other gene-editing techniques. Additionally, these customized cell lines offer reproducibility and reliability in experimental results, providing researchers with a robust platform for experimental design and interpretation.
For researchers and clinicians dedicated to unraveling the complexities of gene function and its implications in health and disease, PSG4 Gene Knockout Cell Lines represent an invaluable resource. They enable rigorous investigation of gene interactions and signaling pathways, paving the way for innovative therapeutic approaches.
As a company dedicated to advancing life sciences research, we pride ourselves on providing high-quality, scientifically validated products that empower our customers. Our expertise in cellular models ensures that our PSG4 Gene Knockout Cell Lines are rigorously developed to meet the needs of the research community.
Please note that all services are for research use only. Not intended for any clinical use.
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