Gene: PSD
Official Full Name: pleckstrin and Sec7 domain containingprovided by HGNC
Gene Summary: This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35869 | PSD Knockout cell line (HeLa) | Human | PSD | 1:3~1:6 | Negative | Online Inquiry |
KO35870 | PSD Knockout cell line (HCT 116) | Human | PSD | 1:2~1:4 | Negative | Online Inquiry |
PSD Gene Knockout Cell Lines are custom-engineered cellular models that allow researchers to study the functional role of specific genes by observing phenotypic changes resulting from their complete inactivation. Utilizing cutting-edge CRISPR/Cas9 genome editing technology, these cell lines provide an essential tool for dissecting complex biological pathways, helping scientists to uncover the intricate mechanisms driving various diseases.
The key function of PSD Gene Knockout Cell Lines lies in their ability to facilitate targeted gene disruptions, enabling researchers to investigate gene function with unprecedented precision. Upon the introduction of the CRISPR/Cas9 system into the host cells, specific genomic sequences associated with the gene of interest are cleaved, leading to mutations that effectively "knock out" gene expression. This allows for direct observation of effects on cellular processes, signaling pathways, and overall cellular health, making these models invaluable in both basic and applied research.
The scientific importance of PSD Gene Knockout Cell Lines extends across numerous applications, including drug discovery, functional genomics, and disease modeling. In clinical research settings, they hold particular promise in elucidating the genetic bases of diseases such as cancer, neurological disorders, and metabolic syndromes, thereby potentially guiding therapeutic interventions.
Compared to alternative gene manipulation approaches, such as RNA interference or traditional chemical mutagens, PSD Gene Knockout Cell Lines offer higher specificity and efficiency in gene targeting. These cell lines maintain genomic integrity post-editing, which minimizes confounding variables during experimentation. Additionally, they are available in various cellular backgrounds relevant to researchers' needs, further enhancing their utility in different experimental contexts.
The value of PSD Gene Knockout Cell Lines extends to researchers and clinicians alike, providing them with an indispensable platform to drive innovation in genetic research. By elucidating the functions of specific genes, these cell lines pave the way for advancements in gene therapy and precision medicine.
As a leading manufacturer in the field of biological products, our company is dedicated to advancing research through high-quality, reliable cell lines that cater to the evolving needs of the scientific community. Our commitment to excellence ensures that our customers can trust our products to deliver consistent results that enhance their research capabilities.
Please note that all services are for research use only. Not intended for any clinical use.
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