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PRUNE1 Knockout Cell Lines

Gene: PRUNE1

Official Full Name: prune exopolyphosphatase 1provided by HGNC

Gene Summary: This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14828 PRUNE1 Knockout cell line (HeLa) Human PRUNE1 1:3~1:6 Negative Online Inquiry
KO14829 PRUNE1 Knockout cell line (HCT 116) Human PRUNE1 1:2~1:4 Negative Online Inquiry
KO14830 PRUNE1 Knockout cell line (HEK293) Human PRUNE1 1:3~1:6 Negative Online Inquiry
KO14831 PRUNE1 Knockout cell line (A549) Human PRUNE1 1:3~1:4 Negative Online Inquiry

Background

PRUNE1 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to study the functional role of the PRUNE1 gene, which encodes a protein known to be involved in various cellular processes, including cell proliferation and apoptosis. This product utilizes sophisticated CRISPR/Cas9 technology to create precise gene disruptions, allowing researchers to investigate the effects of PRUNE1 deficiency on cellular behavior and pathology.

The primary function of the PRUNE1 Gene Knockout Cell Lines lies in their ability to serve as a reliable tool for elucidating the mechanisms underlying PRUNE1-related biological processes. By examining these knockout lines, researchers can explore cellular pathways impacted by the absence of PRUNE1, providing insights into its role in disease states, particularly in cancer biology and neurodegenerative disorders. These models enable effective assessments of drug responses and cellular interactions, facilitating comprehensive research into therapeutic strategies.

The scientific importance of PRUNE1 Gene Knockout Cell Lines is underscored by their relevance in both basic and translational research. As interest grows in the role of non-coding genes in human health, these models offer unique opportunities to correlate genetic alterations with clinical outcomes, making them invaluable for developing targeted therapies and personalized medicine initiatives.

Compared to other gene knockout models, PRUNE1 Gene Knockout Cell Lines stand out due to their specificity, reliability, and ease of use. They are readily available, minimizing the time and resources typically spent on developing custom models. Additionally, these cell lines maintain essential physiological properties, ensuring that experimental outcomes are relevant and replicable.

For researchers and clinicians seeking to enhance their studies in genetics, cell biology, and therapeutic development, PRUNE1 Gene Knockout Cell Lines provide essential insights into gene function and disease mechanisms. By utilizing this product, users can significantly advance their research efforts with confidence and precision.

As a company dedicated to innovation and excellence in genetic research tools, we leverage our extensive expertise in genetic engineering and cell line development to offer high-quality products that cater to the evolving needs of the scientific community.

Please note that all services are for research use only. Not intended for any clinical use.

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