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PRRT4 Knockout Cell Lines

Gene: PRRT4

Official Full Name: proline rich transmembrane protein 4provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO21362 PRRT4 Knockout cell line (HCT 116) Human PRRT4 1:2~1:4 Negative Online Inquiry
KO21363 PRRT4 Knockout cell line (HEK293) Human PRRT4 1:3~1:6 Negative Online Inquiry

Background

PRRT4 Gene Knockout Cell Lines are specially engineered cellular models designed to facilitate the study of the proline-rich transmembrane protein 4 (PRRT4) in a variety of biological contexts. These cell lines are created through targeted genome editing techniques, such as CRISPR-Cas9, resulting in the complete disruption of the PRRT4 gene. This knockout model enables researchers to investigate the gene's function and downstream physiological effects without the influence of PRRT4, offering insights into its role in various cellular processes.

The primary mechanism of action involves the complete abrogation of PRRT4 protein expression, allowing scientists to discern the phenotypic and molecular consequences of its absence. This cellular model is invaluable for studies focused on neurobiology, cellular signaling pathways, and cancer research, where PRRT4 has been implicated in tumor progression and metastasis. By understanding how the loss of PRRT4 influences cellular interactions and gene expression profiles, researchers can identify potential therapeutic targets and develop novel treatment strategies.

One of the significant advantages of using PRRT4 Gene Knockout Cell Lines over traditional models is the precision with which the gene is targeted, minimizing off-target effects that could confound results. Additionally, these cell lines are readily applicable in both in vitro and in vivo studies, thus broadening their utility across various experimental paradigms.

In a research landscape where time and resource efficiency are paramount, the ability to swiftly obtain data from these knockout models directly correlates with accelerated discoveries and innovations. By incorporating PRRT4 Gene Knockout Cell Lines into experimental workflows, researchers and clinicians can harness a powerful tool to advance their understanding of PRRT4-related biological mechanisms, ultimately contributing to the development of novel therapeutics.

With a commitment to scientific excellence, our company specializes in advanced genetic modification technologies, providing researchers with high-quality biological products that are tailored to meet the evolving demands of modern research.

Please note that all services are for research use only. Not intended for any clinical use.

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