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PRRG4 Knockout Cell Lines

Gene: PRRG4

Official Full Name: proline rich and Gla domain 4provided by HGNC

Gene Summary: Enables WW domain binding activity. Predicted to be involved in blood coagulation. Located in plasma membrane. Biomarker of cholangiocarcinoma. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14847 PRRG4 Knockout cell line (HeLa) Human PRRG4 1:3~1:6 Negative Online Inquiry
KO14848 PRRG4 Knockout cell line (HCT 116) Human PRRG4 1:2~1:4 Negative Online Inquiry
KO14849 PRRG4 Knockout cell line (HEK293) Human PRRG4 1:3~1:6 Negative Online Inquiry
KO14850 PRRG4 Knockout cell line (A549) Human PRRG4 1:3~1:4 Negative Online Inquiry

Background

PRRG4 Gene Knockout Cell Lines are sophisticated biological tools designed to facilitate in-depth functional studies of the PRRG4 gene, which is implicated in various cellular processes, including proliferation, differentiation, and apoptosis. These knockout cell lines are generated using advanced CRISPR/Cas9 technology, allowing researchers to achieve precise gene editing by completely disabling the PRRG4 gene in a specific cell type. This targeted approach enables the investigation of gene-specific roles within cellular pathways and responses to various stimuli.

The primary function of PRRG4 Gene Knockout Cell Lines is to provide a controlled environment where the effects of the absence of the PRRG4 gene can be assessed. This can elucidate mechanisms underlying disease states, particularly in conditions like cancer, where deregulation of growth and apoptosis is crucial. By studying these cells, researchers can discern how the loss of PRRG4 affects signaling pathways and cellular behaviors, thereby generating insights into potential therapeutic targets.

In both research and clinical settings, these cell lines serve as invaluable models for drug testing and development, allowing scientists to understand how PRRG4 knockout influences drug efficacy and cellular responses. Compared to conventional methods, the gene knockout approach offers more consistent and reproducible results, as it eliminates confounding variables associated with incomplete knockdowns or overexpressed compensatory pathways.

The unique selling points of PRRG4 Gene Knockout Cell Lines include their ease of use, reliability in experimental setups, and the robustness of data generated from their application. These cell lines are characterized by a high degree of specificity, providing a more authentic representation of biological behaviors than traditional methods, making them an advantageous choice for laboratories focused on cutting-edge genetic research.

For researchers, clinicians, or biotechnologists interested in the functional analysis of gene roles, these knockout cell lines present a powerful resource. As leaders in the development of genetically engineered models, our company is committed to delivering top-tier biological products that empower scientific discovery and innovation. By integrating our expertise with pioneering technologies, we help advance research and therapeutic approaches in genetics and molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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