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PRPSAP1 Knockout Cell Lines

Gene: PRPSAP1

Official Full Name: phosphoribosyl pyrophosphate synthetase associated protein 1provided by HGNC

Gene Summary: Enables identical protein binding activity. Predicted to be involved in 5-phosphoribose 1-diphosphate biosynthetic process and purine nucleotide biosynthetic process. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35888 PRPSAP1 Knockout cell line (HeLa) Human PRPSAP1 1:3~1:6 Negative Online Inquiry
KO35889 PRPSAP1 Knockout cell line (HCT 116) Human PRPSAP1 1:2~1:4 Negative Online Inquiry
KO35890 PRPSAP1 Knockout cell line (HEK293) Human PRPSAP1 1:3~1:6 Negative Online Inquiry
KO35891 PRPSAP1 Knockout cell line (A549) Human PRPSAP1 1:3~1:4 Negative Online Inquiry

Background

PRPSAP1 Gene Knockout Cell Lines are advanced cellular models specifically engineered to study the impact of the PRPSAP1 gene, which encodes a regulatory protein involved in purine metabolism. By creating knockout models, researchers can effectively eliminate the expression of PRPSAP1, enabling the investigation of its physiological roles and involvement in various biological processes.

The primary function of these cell lines revolves around their ability to provide insights into the cellular responses when PRPSAP1 is absent. This is achieved through sophisticated CRISPR-Cas9 gene editing techniques, which ensure precise and efficient gene disruption. The resulting cellular environment mimics the pathological conditions related to PRPSAP1 dysfunction, facilitating exploratory research into metabolic disorders, cancer biology, and neurodegenerative diseases associated with nucleotide metabolism abnormalities.

The scientific importance of PRPSAP1 Gene Knockout Cell Lines lies in their wide-ranging applications in both research and clinical settings. They furnish a robust platform for drug discovery, biomarker identification, and functional genomics studies, particularly in elucidating the pathways that govern cellular proliferation and stress response mechanisms. Their capability to model disease states offers researchers invaluable tools for therapeutic target validation.

Unlike other genomic models, PRPSAP1 Gene Knockout Cell Lines stand out due to their high fidelity and reproducibility, ensuring that experimental results are consistent and reliable. Such precision is critical in the context of translational research, where the accuracy of cellular responses can significantly influence therapeutic outcomes.

The value of this product extends beyond the laboratory; it caters to researchers, pharmaceutical developers, and clinical scientists seeking to deepen their understanding of purine metabolism and its implications in health and disease. By utilizing these knockout cell lines, users can advance their research with confidence, paving the way for the development of innovative treatments.

Our company prides itself on its dedication to providing high-quality biological products, underpinned by extensive expertise in genetic engineering and cell line development. With a commitment to advancing scientific discovery, we empower researchers to unlock the complexities of cellular functions and contribute toward groundbreaking solutions in medicine and biology.

Please note that all services are for research use only. Not intended for any clinical use.

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