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PROX1 Knockout Cell Lines

Gene: PROX1

Official Full Name: prospero homeobox 1provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03186 PROX1 Knockout cell line (HEK293) Human PROX1 1:3~1:6 Negative Online Inquiry

Background

PROX1 Gene Knockout Cell Lines are sophisticated cellular models designed specifically for the study of the PROX1 gene, a crucial player in various biological processes, including lymphangiogenesis, neurogenesis, and organ development. These knockout cell lines are generated using advanced CRISPR/Cas9 gene-editing technology, meticulously removing or disabling the PROX1 gene to provide a clear understanding of its function and role in health and disease.

The primary function of these cell lines is to serve as a platform for comprehensive genetic, biochemical, and therapeutic investigations. By utilizing these knockout models, researchers can elucidate the pathways influenced by PROX1, identify gene interactions, and investigate the gene's involvement in pathological conditions such as cancer progression or developmental disorders. This mechanistic insight is invaluable in designing targeted therapies or novel diagnostic approaches.

The scientific importance of PROX1 Gene Knockout Cell Lines extends to both research and clinical applications. In research settings, they enable investigators to delve into the molecular underpinnings of diseases linked to aberrant PROX1 expression, facilitating the exploration of therapeutic interventions. Clinically, understanding the role of PROX1 in tumor biology could pave the way for innovative treatments that target lymphatic and vascular anomalies.

Compared to conventional cell lines, PROX1 Gene Knockout Cell Lines offer distinct advantages. They provide a more precise representation of the biological phenomena associated with gene deletion, allowing for clearer interpretation of experimental data. Moreover, these models minimize background interference from functional PROX1, offering researchers a unique tool to investigate gene-specific consequences reliably.

The value of PROX1 Gene Knockout Cell Lines for researchers and clinicians cannot be overstated; they provide a critical resource for advancing scientific knowledge while igniting the potential for groundbreaking therapeutic solutions. Our company prides itself on delivering high-quality biological products backed by robust scientific expertise and innovative methodologies. We are committed to supporting the scientific community by providing tools that facilitate impactful research and clinical advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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