Gene: PRMT7
Official Full Name: protein arginine methyltransferase 7provided by HGNC
Gene Summary: This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients. [provided by RefSeq, May 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14882 | PRMT7 Knockout cell line (HeLa) | Human | PRMT7 | 1:3~1:6 | Negative | Online Inquiry |
KO14883 | PRMT7 Knockout cell line (HCT 116) | Human | PRMT7 | 1:2~1:4 | Negative | Online Inquiry |
KO14884 | PRMT7 Knockout cell line (HEK293) | Human | PRMT7 | 1:3~1:6 | Negative | Online Inquiry |
KO14885 | PRMT7 Knockout cell line (A549) | Human | PRMT7 | 1:3~1:4 | Negative | Online Inquiry |
PRMT7 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically modified to disrupt the expression of the PRMT7 gene, a member of the protein arginine methyltransferase family. This product enables researchers to study the biological roles and functional significance of PRMT7 in various cellular processes, including gene expression regulation, signal transduction, and protein-protein interactions. By effectively silencing PRMT7, these cell lines facilitate in-depth investigations into the mechanisms of arginine methylation and its implications in cell growth, differentiation, and disease.
The primary mechanism of action involves the targeted deletion of the PRMT7 gene, creating a knockout model that allows scientists to observe the effects of the absence of PRMT7. This provides a valuable platform for identifying downstream targets and elucidating the pathway networks influenced by this enzyme. Additionally, PRMT7 has been implicated in cancer biology and other chronic diseases, making knockout cell lines essential tools for discovering potential therapeutic strategies and novel biomarkers.
The scientific importance of PRMT7 Gene Knockout Cell Lines extends into both research and clinical settings. In research, they serve as critical tools for unraveling the pathogenic pathways associated with dysregulated arginine methylation, while in clinical applications, understanding PRMT7's role can contribute to developing targeted therapies for conditions linked to aberrant methylation patterns.
What sets these cell lines apart from alternatives is their precision, reliability, and the comprehensive characterization of the knockout model. These characteristics ensure reproducibility and confidence in experimental outcomes, critical factors in high-stakes research environments. Additionally, these cell lines come with detailed lineage information and validation data, offering researchers peace of mind when incorporating them into their experiments.
For researchers and clinicians focused on gene regulation, epigenetics, and cancer biology, the availability of PRMT7 Gene Knockout Cell Lines is invaluable. Access to these tools enhances the potential for groundbreaking discoveries and fosters innovation in therapeutic approach development.
Our company specializes in providing cutting-edge biological tools designed to accelerate research and deliver clearer insights into gene function and regulation. With our extensive expertise in genetic engineering and cell line development, we are committed to supporting the scientific community with high-quality products tailored to meet evolving research needs.
Please note that all services are for research use only. Not intended for any clinical use.
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