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PREPL Knockout Cell Lines

Gene: PREPL

Official Full Name: prolyl endopeptidase likeprovided by HGNC

Gene Summary: The protein encoded by this gene belongs to the prolyl oligopeptidase subfamily of serine peptidases. Mutations in this gene have been associated with hypotonia-cystinuria syndrome, also known as the 2p21 deletion syndrome. Several alternatively spliced transcript variants encoding either the same or different isoforms have been described for this gene.[provided by RefSeq, Jan 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33079 PREPL Knockout cell line (HeLa) Human PREPL 1:3~1:6 Negative Online Inquiry
KO33080 PREPL Knockout cell line (HCT 116) Human PREPL 1:2~1:4 Negative Online Inquiry
KO33081 PREPL Knockout cell line (HEK293) Human PREPL 1:3~1:6 Negative Online Inquiry
KO33082 PREPL Knockout cell line (A549) Human PREPL 1:3~1:4 Negative Online Inquiry

Background

PREPL Gene Knockout Cell Lines represent a highly specialized tool for researchers working in the field of genetics and molecular biology. These cell lines are engineered to have targeted deletions of the PREPL gene, a critical component involved in various cellular processes, including protein metabolism and signaling pathways. By eliminating the PREPL gene, scientists can investigate the downstream effects on cellular function, thereby elucidating its role in health and disease.

The primary mechanism of action for PREPL Gene Knockout Cell Lines involves the use of CRISPR/Cas9 technology, which allows for precise genomic editing. This cutting-edge approach results in the creation of stable cell lines that lack the PREPL gene, enabling researchers to study gene function, validate disease models, and test therapeutic strategies with high specificity and reproducibility.

In terms of scientific importance, PREPL Gene Knockout Cell Lines are invaluable in research settings focused on understanding neurological disorders and metabolic diseases associated with PREPL dysfunction. They serve as essential tools for drug discovery, allowing clinicians and researchers to evaluate potential treatments in a controlled environment. Furthermore, these cell lines facilitate the study of gene interactions, offering insights into the complex regulatory networks that govern cellular behavior.

What sets PREPL Gene Knockout Cell Lines apart from traditional cell models is their unparalleled specificity and the ease of use they afford the research community. Unlike other gene editing methods, CRISPR/Cas9 provides not just knockout efficiency but also greater flexibility and lower off-target effects, making these cell lines a preferred choice for rigorous scientific investigation.

For researchers and clinicians aiming to advance their work in genetic and cellular biology, PREPL Gene Knockout Cell Lines offer a unique and robust platform that can drastically enhance their experimental capabilities. By choosing our product, you gain access to a reliable, scientifically validated model designed to propel your research forward.

As a company dedicated to delivering innovative biological products, we leverage state-of-the-art technologies to provide high-quality, customizable cell line solutions that empower researchers and clinicians alike in their quest for scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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