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PRDX1 Knockout Cell Lines

Gene: PRDX1

Official Full Name: peroxiredoxin 1provided by HGNC

Gene Summary: This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01541 PRDX1 Knockout cell line (HeLa) Human PRDX1 1:3~1:6 Negative Online Inquiry
KO01542 PRDX1 Knockout cell line (HCT 116) Human PRDX1 1:2~1:4 Negative Online Inquiry
KO01543 PRDX1 Knockout cell line (HEK293) Human PRDX1 1:3~1:6 Negative Online Inquiry
KO01544 PRDX1 Knockout cell line (A549) Human PRDX1 1:3~1:4 Negative Online Inquiry

Background

PRDX1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the PRDX1 gene, which encodes the enzyme peroxiredoxin 1, a crucial component in regulating cellular redox states and mitigating oxidative stress. By deactivating the PRDX1 gene, these cell lines serve as powerful tools for investigating the role of oxidative stress and redox signaling in various biological processes.

The primary function of PRDX1 is to reduce peroxide levels within cells, thereby protecting them from oxidative damage. The knockout of this gene leads to increased sensitivity to oxidative stress, enabling researchers to study the consequences of unregulated reactive oxygen species (ROS) in both physiological and pathological contexts. Through these cell lines, scientists can explore mechanisms underlying various diseases, including neurodegeneration, cancer, and inflammatory conditions, where oxidative stress plays a pivotal role.

Scientifically, PRDX1 Gene Knockout Cell Lines hold immense value in elucidating the complexities of redox biology, which is critical for developing targeted therapies. These models allow researchers and clinicians to pinpoint the therapeutic potential of antioxidant strategies and enhance our understanding of diseases where redox imbalance is a hallmark.

What sets these knockout cell lines apart from alternatives is their specificity and reliability, given that they are rigorously validated for consistent genetic and phenotypic characteristics. These unique features allow for reproducible results in experimental settings, which is crucial for yielding credible data and advancing scientific knowledge.

The value of utilizing PRDX1 Gene Knockout Cell Lines lies in their capacity to accelerate the discovery of novel insights, paving the way for innovative treatments for oxidative stress-related conditions. By choosing our specialized lines, researchers and clinicians benefit from our uncompromising commitment to quality and our extensive experience in genetic engineering. Our expertise ensures that each product meets the highest standards, enabling scientists to push the boundaries of discovery with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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