Gene: PRDM6
Official Full Name: PR/SET domain 6provided by HGNC
Gene Summary: The protein encoded by this gene is a transcriptional repressor and a member of the PRDM family. Family members contain a PR domain and multiple zinc-finger domains. The encoded protein is involved in regulation of vascular smooth muscle cells (VSMC) contractile proteins. Mutations in this gene result in patent ductus arteriosus 3 (PDA3). [provided by RefSeq, Apr 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22286 | PRDM6 Knockout cell line (HeLa) | Human | PRDM6 | 1:3~1:6 | Negative | Online Inquiry |
KO22287 | PRDM6 Knockout cell line (HEK293) | Human | PRDM6 | 1:3~1:6 | Negative | Online Inquiry |
PRDM6 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to disable the PRDM6 gene, which encodes a protein involved in diverse biological processes, including cell differentiation and response to stress. The knockout of this gene can lead to profound changes in cellular behavior, making these cell lines invaluable tools for investigating the physiological roles of PRDM6 in various models of disease and development.
The key function of PRDM6 gene knockout cell lines revolves around their ability to facilitate the study of gene function by creating a controlled environment where the effects of gene loss can be systematically examined. These cell lines utilize advanced CRISPR-Cas9 gene-editing technology, enabling the targeted disruption of the PRDM6 gene to observe resultant phenotypic changes and molecular pathways directly related to its activity. This allows researchers to delve into the mechanisms underlying diseases such as cancer, cardiovascular disorders, and metabolic syndromes.
In the realm of scientific importance, the applications of PRDM6 gene knockout cell lines extend to both basic research and translational medicine. They serve as platforms for drug discovery, enabling the assessment of therapeutic responses in cells lacking specific gene function. Additionally, they provide insights into developmental biology by helping scientists explore roles of PRDM6 in stem cell biology and lineage specification.
Compared to conventional methods, PRDM6 gene knockout cell lines offer a precise and reproducible means of studying gene function with lower off-target effects. Their unique selling points include the enhancement of specificity in experimental designs and the ability to generate stable, long-term cell culture systems.
For researchers and clinicians seeking deeper insights into gene function and its implications in health and disease, PRDM6 gene knockout cell lines represent an essential resource. They empower investigations that may lead to novel therapeutic strategies and a better understanding of gene regulation.
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Please note that all services are for research use only. Not intended for any clinical use.
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