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PRDM1 Knockout Cell Lines

Gene: PRDM1

Official Full Name: PR/SET domain 1provided by HGNC

Gene Summary: This gene encodes a protein that acts as a repressor of beta-interferon gene expression. The protein binds specifically to the PRDI (positive regulatory domain I element) of the beta-IFN gene promoter. Transcription of this gene increases upon virus induction. Two alternatively spliced transcript variants that encode different isoforms have been reported. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38812 PRDM1 Knockout cell line (HeLa) Human PRDM1 1:3~1:6 Negative Online Inquiry
KO38813 PRDM1 Knockout cell line (HCT 116) Human PRDM1 1:2~1:4 Negative Online Inquiry
KO38814 PRDM1 Knockout cell line (A549) Human PRDM1 1:3~1:4 Negative Online Inquiry

Background

PRDM1 Gene Knockout Cell Lines are engineered cellular models specifically designed to facilitate in-depth studies of PRDM1, a critical gene involved in immunological processes and cell differentiation. PRDM1, also known as BLIMP-1, is pivotal in regulating B cell differentiation and has implications in autoimmune diseases and various malignancies. These knockout cell lines effectively eliminate the expression of the PRDM1 gene, enabling researchers to analyze the downstream effects and functional consequences of its absence.

The primary function of these cell lines is to provide a controlled environment for investigating the genetic and molecular pathways influenced by PRDM1. By observing cell behavior in the absence of PRDM1, researchers can uncover critical insights into B cell maturation and the broader implications of immune responses. The cell lines can be utilized for high-throughput screening, gene expression analysis, and therapeutic studies, making them invaluable tools in the pursuit of novel treatments and interventions.

The scientific importance of PRDM1 Gene Knockout Cell Lines cannot be overstated; they offer significant applications in both basic and translational research settings. Their use in studying immune cell populations can lead to advanced understanding of immune disorders, while their application in cancer research helps illuminate potential therapeutic targets and biomarkers.

Compared to other conventional models, the unique selling points of these knockout cell lines include their specificity and reproducibility. They are generated using advanced genomic engineering techniques, ensuring high fidelity in gene deletion and enabling consistent results across experiments. This reliability translates into more actionable data, making the decision-making process in research and clinical applications much more efficient.

For researchers and clinicians focused on immunology, oncology, and genetic research, PRDM1 Gene Knockout Cell Lines offer a robust platform for discovering the nuances of PRDM1's role in health and disease. By exploiting these lines, users can enhance their understanding and possibly uncover new avenues for therapeutic intervention.

Our company specializes in providing high-quality biological research tools, and we are dedicated to supporting scientists and clinicians with cutting-edge products like the PRDM1 Gene Knockout Cell Lines to drive innovation in biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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