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PRAG1 Knockout Cell Lines

Gene: PRAG1

Official Full Name: PEAK1 related, kinase-activating pseudokinase 1provided by HGNC

Gene Summary: This gene encodes an enzyme that belongs to the tyrosine protein kinase family. A similar protein in rat binds to Rho family GTPase 2 (Rnd2) and regulates neurite outgrowth via activation of Ras homolog gene family, member A (RhoA). [provided by RefSeq, Mar 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14908 PRAG1 Knockout cell line (HeLa) Human PRAG1 1:3~1:6 Negative Online Inquiry
KO14909 PRAG1 Knockout cell line (HCT 116) Human PRAG1 1:2~1:4 Negative Online Inquiry
KO14910 PRAG1 Knockout cell line (HEK293) Human PRAG1 1:3~1:6 Negative Online Inquiry
KO14911 PRAG1 Knockout cell line (A549) Human PRAG1 1:3~1:4 Negative Online Inquiry

Background

PRAG1 Gene Knockout Cell Lines represent a cutting-edge tool in the field of molecular biology, specifically engineered to elucidate the functional roles of the PRAG1 gene. These cell lines have been meticulously developed through CRISPR-Cas9 gene editing technology, creating a knockout of the PRAG1 gene, which allows researchers to investigate its involvement in various cellular processes, including cell proliferation, differentiation, and response to stress.

The key mechanism of action involves the targeted disruption of the PRAG1 gene, leading to a loss of function that can be assessed through comparative analyses with wild-type cell lines. This provides researchers with an invaluable opportunity to study the phenotypic and biochemical changes that occur in the absence of PRAG1, thereby gaining insights into its role in disease mechanisms and cellular signaling pathways.

The scientific importance of PRAG1 Gene Knockout Cell Lines extends across a range of research applications, including cancer biology, regenerative medicine, and neurobiology. Researchers can leverage these models to explore how PRAG1 influences cellular dynamics and its potential implications in therapeutic strategies. Additionally, these cell lines serve as essential tools in drug discovery and validation processes, enabling the identification of new therapeutic targets.

There are significant advantages to utilizing PRAG1 Gene Knockout Cell Lines over traditional methods like RNA interference, which may offer transient effects or off-target results. Our knockout cell lines deliver robust and stable gene disruption, ensuring consistent and reproducible experimental outcomes. This specificity enhances the reliability of research findings, ultimately accelerating the pace of discovery.

For researchers and clinicians seeking to deepen their understanding of PRAG1's biological functions and its implications in health and disease, these cell lines are an indispensable resource. By choosing PRAG1 Gene Knockout Cell Lines, you are investing in a powerful model system that will enhance the rigor and relevance of your studies.

As pioneers in the field of engineered biological products, our company is dedicated to providing advanced research tools that empower scientists to push the boundaries of knowledge and innovation. We are committed to enhancing your research capabilities with precision-engineered solutions designed for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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