Gene: PPP2R5D
Official Full Name: protein phosphatase 2 regulatory subunit B'deltaprovided by HGNC
Gene Summary: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO10169 | PPP2R5D Knockout cell line (HeLa) | Human | PPP2R5D | 1:3~1:6 | Negative | Online Inquiry |
KO10170 | PPP2R5D Knockout cell line (HCT 116) | Human | PPP2R5D | 1:2~1:4 | Negative | Online Inquiry |
KO10171 | PPP2R5D Knockout cell line (HEK293) | Human | PPP2R5D | 1:3~1:6 | Negative | Online Inquiry |
KO10172 | PPP2R5D Knockout cell line (A549) | Human | PPP2R5D | 1:3~1:4 | Negative | Online Inquiry |
PPP2R5D Gene Knockout Cell Lines are specialized cellular models designed to elucidate the functional roles of the PPP2R5D gene, known for its involvement in crucial cellular processes such as signal transduction, cell cycle regulation, and apoptosis. By employing CRISPR/Cas9 technology, these knockout cell lines are created to disable the expression of the PPP2R5D gene, thereby providing researchers with an invaluable tool to analyze the gene's pathways and its implications in various diseases, particularly cancer.
The principal function of the PPP2R5D Gene Knockout Cell Lines lies in their ability to mimic specific pathogenic conditions under controlled experimental environments. This is achieved by observing the altered signaling pathways and cellular behaviors resulting from the absence of PPP2R5D, allowing for comprehensive investigation into its regulatory mechanisms. Researchers can use these cell lines to study how the loss of PPP2R5D affects phosphatase activity, metabolic profiles, and overall cell signaling, ultimately unveiling potential therapeutic targets.
Scientifically, these knockout cell lines hold significant importance in both basic and translational research. Their application extends to studying tumorigenesis mechanisms, drug resistance, and the development of targeted therapies. Furthermore, because PPP2R5D has been implicated in various neurodevelopmental disorders, these cell lines can also contribute to understanding the genetic underpinnings of such conditions.
Compared to other models, the unique selling points of the PPP2R5D Gene Knockout Cell Lines include their specificity, reliability, and ease of use. Unlike traditional methods, which may yield variable results or require extensive optimization, our cell lines offer a streamlined approach that accelerates experimental timelines and enhances reproducibility. Additionally, their groundwork in CRISPR technology ensures precise genetic modification, reducing off-target effects and elevating confidence in experimental outcomes.
Researchers and clinicians seeking deeper insights into cellular signaling networks will find exceptional value in these knockout cell lines. Their integration into diverse experimental frameworks can expand our understanding of the PPP2R5D gene's role in health and disease, thereby accelerating the development of therapeutic interventions.
Our company specializes in delivering cutting-edge biological products. With a strong foundation in genetic engineering and a commitment to quality, we are dedicated to providing tools like the PPP2R5D Gene Knockout Cell Lines that empower the scientific community to push the boundaries of discovery.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.