Gene: PPP1R12C
Official Full Name: protein phosphatase 1 regulatory subunit 12Cprovided by HGNC
Gene Summary: The gene encodes a subunit of myosin phosphatase. The encoded protein regulates the catalytic activity of protein phosphatase 1 delta and assembly of the actin cytoskeleton. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03299 | PPP1R12C Knockout cell line (HeLa) | Human | PPP1R12C | 1:3~1:6 | Negative | Online Inquiry |
KO03300 | PPP1R12C Knockout cell line (HCT 116) | Human | PPP1R12C | 1:2~1:4 | Negative | Online Inquiry |
KO03301 | PPP1R12C Knockout cell line (HEK293) | Human | PPP1R12C | 1:3~1:6 | Negative | Online Inquiry |
KO03302 | PPP1R12C Knockout cell line (A549) | Human | PPP1R12C | 1:3~1:4 | Negative | Online Inquiry |
PPP1R12C Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to lack the PPP1R12C gene, which encodes the protein phosphatase 1 regulatory subunit 12C. These knockout cell lines serve as valuable tools for studying the role and function of PPP1R12C in various biological processes, including signal transduction, cellular proliferation, and apoptosis. By creating a controlled environment free of this protein, researchers can more accurately investigate its downstream effects on cell behavior and interaction with other signaling molecules.
Mechanistically, the absence of the PPP1R12C protein allows for the elucidation of its regulatory effects on protein phosphatase 1 (PP1), emphasizing its role in modulating key post-translational modifications that drive cellular functions. The versatile nature of these knockout cell lines makes them ideal for applications in basic research as well as in drug discovery and development, where understanding the precise molecular mechanisms impacted by PPP1R12C can lead to therapeutic advancements.
The scientific importance of the PPP1R12C Gene Knockout Cell Lines is underscored by their ability to contribute to the growing body of knowledge in cancer biology, neurobiology, and metabolic disorders, facilitating the identification of novel intervention points for targeted therapies. Compared to other gene-editing techniques or cell lines that only partially knock down gene expression, these knockout lines provide a more definitive model for examining gene function, thereby enhancing the reliability of experimental results.
For researchers and clinicians, the availability of these knockout cell lines offers unparalleled advantage by providing an accurate representation of the genetic absence, which aids in better experimental design and more robust conclusions. Furthermore, our company's commitment to quality and precision in creating these tools is backed by a team of experienced scientists who understand the intricacies of biological research, ensuring that our products meet high scientific standards and fulfill the specific needs of our users. Investing in PP1R12C Gene Knockout Cell Lines means equipping your research with essential, dependable resources that drive forward scientific inquiry and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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