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PPM1M Knockout Cell Lines

Gene: PPM1M

Official Full Name: protein phosphatase, Mg2+/Mn2+ dependent 1Mprovided by HGNC

Gene Summary: Predicted to enable [pyruvate dehydrogenase (acetyl-transferring)]-phosphatase activity and manganese ion binding activity. Predicted to be involved in protein dephosphorylation and signal transduction. Predicted to be located in nucleus. Predicted to be active in mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26535 PPM1M Knockout cell line (HeLa) Human PPM1M 1:3~1:6 Negative Online Inquiry
KO26536 PPM1M Knockout cell line (HCT 116) Human PPM1M 1:2~1:4 Negative Online Inquiry
KO26537 PPM1M Knockout cell line (HEK293) Human PPM1M 1:3~1:6 Negative Online Inquiry
KO26538 PPM1M Knockout cell line (A549) Human PPM1M 1:3~1:4 Negative Online Inquiry

Background

PPM1M Gene Knockout Cell Lines are specialized cellular models created to study the functional implications of the PPM1M gene, which encodes a type of protein phosphatase involved in numerous signaling pathways. These cell lines are engineered using advanced CRISPR/Cas9 technology to disrupt the PPM1M gene, allowing researchers to investigate the biological roles of this phosphatase in cellular processes, including cell proliferation, differentiation, and apoptosis.

The primary function of PPM1M Gene Knockout Cell Lines is to provide a platform for examining the consequences of PPM1M loss on various signaling cascades, particularly those related to stress responses and metabolic regulation. By knocking out this gene, scientists can elucidate its role in both normal physiology and disease states, paving the way for better understanding of conditions such as cancer and metabolic disorders. The mechanistic insights gained from using these models can guide the development of targeted therapies and diagnostic tools.

In terms of scientific importance, PPM1M Gene Knockout Cell Lines serve as a crucial resource in both academic and clinical research settings. They facilitate the identification of novel therapeutic targets and enable drug-sensitivity assays, thus proving invaluable to pharmaceutical development processes. Furthermore, these cell lines stand out among alternatives by offering greater specificity and consistency in gene editing, reducing off-target effects commonly associated with previous methodologies.

Researchers and clinicians will find significant value in PPM1M Gene Knockout Cell Lines due to their ability to provide accurate and reproducible data that informs hypotheses and experimental designs. The user-friendly nature of these cell lines, combined with their robust performance, makes them an essential tool for anyone looking to advance their understanding of gene function and its implications in human health.

With a proven track record in producing high-quality biological products, our company is dedicated to supporting scientific innovation and discovery. Our PPM1M Gene Knockout Cell Lines exemplify our commitment to providing researchers with reliable tools essential for groundbreaking research.

Please note that all services are for research use only. Not intended for any clinical use.

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