Gene: PPIL6
Official Full Name: peptidylprolyl isomerase like 6provided by HGNC
Gene Summary: Predicted to enable RNA polymerase II CTD heptapeptide repeat P3 isomerase activity; RNA polymerase II CTD heptapeptide repeat P6 isomerase activity; and cyclosporin A binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14952 | PPIL6 Knockout cell line (HCT 116) | Human | PPIL6 | 1:2~1:4 | Negative | Online Inquiry |
KO14953 | PPIL6 Knockout cell line (A549) | Human | PPIL6 | 1:3~1:4 | Negative | Online Inquiry |
PPIL6 Gene Knockout Cell Lines are specifically engineered cellular models designed to investigate the functional role of the PPIL6 gene in various biological processes. Utilizing CRISPR-Cas9 genome-editing technology, these cell lines have been meticulously created to achieve a complete knockout of the PPIL6 gene, thereby facilitating the study of its impact on protein interactions, cellular signaling pathways, and overall cellular physiology.
The key mechanism behind these knockout cell lines involves the precise deletion of the PPIL6 gene, resulting in the absence of the corresponding protein product. This allows researchers to observe the consequent effects on cellular behavior and responsiveness to external stimuli, providing insights into the gene’s involvement in processes such as splicing and stress response mechanisms. The ability to modulate gene expression in this manner is fundamental for elucidating the molecular basis of various diseases and can contribute to the identification of potential therapeutic targets.
The scientific importance of PPIL6 Gene Knockout Cell Lines lies in their applications across various research fields, such as cancer biology, neurobiology, and immunology. By examining how the absence of PPIL6 affects cell proliferation, differentiation, and apoptosis, researchers can uncover novel mechanisms of disease progression and identify biomarkers that can lead to more effective treatment strategies.
Compared to conventional methods, such as RNA interference, PPIL6 Gene Knockout Cell Lines provide a more stable and permanent disruption of gene function, allowing for extended studies without the variability and transient effects associated with RNAi approaches. These engineered cell lines are also highly scalable, making them suitable for high-throughput screening applications.
For researchers and clinicians, the availability of PPIL6 Gene Knockout Cell Lines represents a pivotal resource for advancing scientific knowledge and developing innovative therapeutic approaches. The value of this product lies not only in its capacity to accelerate discovery but also in the improved clarity it provides in understanding complex genetic interactions.
Our company specializes in the development of cutting-edge biological products, leveraging advanced genetic engineering techniques to support researchers in their quest to uncover the underlying mechanisms of human health and disease. With a commitment to quality, reliability, and scientific rigor, we are dedicated to empowering the research community with state-of-the-art tools that foster innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.