Home / PPIF Knockout Cell Lines

PPIF Knockout Cell Lines

Gene: PPIF

Official Full Name: peptidylprolyl isomerase Fprovided by HGNC

Gene Summary: The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
GP00388 PPIF gRNA1-gRNA2 KO plasmid PPIF $850
KO00688 PPIF Knockout cell line(Caco-2) Human PPIF 1:2~1:4 Negative Online Inquiry
KO07990 PPIF Knockout cell line (HeLa) Human PPIF 1:3~1:6 Negative Online Inquiry
KO07991 PPIF Knockout cell line (HCT 116) Human PPIF 1:2~1:4 Negative Online Inquiry
KO07992 PPIF Knockout cell line (HEK293) Human PPIF 1:3~1:6 Negative Online Inquiry
KO07993 PPIF Knockout cell line (A549) Human PPIF 1:3~1:4 Negative Online Inquiry

Background

PPIF Gene Knockout Cell Lines are specialized biological tools designed to facilitate in-depth studies of the PPIF gene's functions and its implications in cellular processes. These cell lines have been engineered using advanced CRISPR/Cas9 technology to specifically disable the PPIF gene, which encodes the protein p53-induced protein factor. By achieving a selective knockout, researchers can effectively dissect the biological pathways influenced by PPIF and investigate its role in various pathological conditions, including cancer, neurodegenerative diseases, and metabolic disorders.

The key mechanisms of these cell lines involve the precise elimination of PPIF expression, enabling the assessment of downstream effects on cell viability, apoptosis, and metabolic pathways. Through targeted experiments, scientists can observe alterations in cellular responses, protein interactions, and gene expression profiles, thus gaining valuable insights into the underlying mechanisms of diseases associated with PPIF.

With significant scientific importance, PPIF Gene Knockout Cell Lines serve as an essential resource in both basic and applied biomedical research. They provide critical data that can lead to the development of novel therapeutic strategies, allowing clinicians to explore potential interventions that target PPIF-related dysregulation.

Distinctively, these cell lines stand out from traditional methods of gene manipulation due to their high specificity, efficiency, and reproducibility. Researchers benefit from a streamlined process that minimizes off-target effects, supporting high-confidence experimental outcomes. This specificity is invaluable in elucidating precise cellular functions tied to the PPIF gene.

In a landscape where researchers and clinicians are continually seeking innovative solutions to complex biological questions, PPIF Gene Knockout Cell Lines offer unmatched value. Their application can accelerate discoveries, enabling a thorough understanding of PPIF's role in health and disease.

Our company is dedicated to providing high-quality biological products tailored for cutting-edge research, leveraging extensive expertise in molecular biology and genetics to deliver reliable tools that enhance scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.