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POC5 Knockout Cell Lines

Gene: POC5

Official Full Name: POC5 centriolar proteinprovided by HGNC

Gene Summary: Predicted to be involved in eye photoreceptor cell development. Located in centrosome; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26446 POC5 Knockout cell line (HeLa) Human POC5 1:3~1:6 Negative Online Inquiry
KO26447 POC5 Knockout cell line (HCT 116) Human POC5 1:2~1:4 Negative Online Inquiry
KO26448 POC5 Knockout cell line (HEK293) Human POC5 1:3~1:6 Negative Online Inquiry
KO26449 POC5 Knockout cell line (A549) Human POC5 1:3~1:4 Negative Online Inquiry

Background

POC5 Gene Knockout Cell Lines is a specialized biological product designed for advanced genetic research and therapeutic development. These cell lines feature a complete knockout of the POC5 gene, which plays a crucial role in maintaining centriolar structure and function. By using CRISPR-Cas9 technology, the POC5 gene has been specifically targeted and disrupted, allowing researchers to study the consequences of its absence on cellular behavior, mitotic processes, and ciliogenesis.

The primary function of the POC5 Gene Knockout Cell Lines is to serve as a versatile tool for investigating the implications of POC5 in cell division and disease pathology. The absence of POC5 can lead to aberrant cell division and compromised cellular structures, providing a clear model for studying cancer biology and developmental disorders. Additionally, these cell lines enable the exploration of potential therapeutic targets, as understanding the role of POC5 may reveal novel interventions for diseases characterized by defective centriole function.

One of the standout advantages of the POC5 Gene Knockout Cell Lines is their specificity and reproducibility compared to previous gene-editing methods. This precise targeting minimizes off-target effects, ensuring that the observed phenotypical changes are directly attributable to the gene knockout. Researchers can confidently rely on these cell lines for their experiments, ultimately leading to more reliable and impactful results.

These cell lines are invaluable to both academic researchers and clinicians working at the forefront of genetic and cellular studies. By providing a clear model for investigating the pathophysiological roles of POC5, they contribute significantly to the understanding of various diseases and accelerate the development of innovative treatments.

As a leader in the field of genetic engineering and cellular products, our company is committed to delivering high-quality research tools. We leverage cutting-edge technology to produce advanced biological products that empower scientists and healthcare professionals to achieve groundbreaking outcomes in their respective fields.

Please note that all services are for research use only. Not intended for any clinical use.

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