Gene: PNRC1
Official Full Name: proline rich nuclear receptor coactivator 1provided by HGNC
Gene Summary: Predicted to be involved in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay. Predicted to be active in P-body and nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31374 | PNRC1 Knockout cell line (HeLa) | Human | PNRC1 | 1:3~1:6 | Negative | Online Inquiry |
KO31375 | PNRC1 Knockout cell line (HCT 116) | Human | PNRC1 | 1:2~1:4 | Negative | Online Inquiry |
KO31376 | PNRC1 Knockout cell line (HEK293) | Human | PNRC1 | 1:3~1:6 | Negative | Online Inquiry |
KO31377 | PNRC1 Knockout cell line (A549) | Human | PNRC1 | 1:3~1:4 | Negative | Online Inquiry |
PNRC1 Gene Knockout Cell Lines are genetically modified cell lines designed to facilitate in-depth studies of the PNRC1 gene, known for its role in various cellular processes, including RNA metabolism and stress responses. By employing CRISPR-Cas9 technology, these knockout cell lines provide a reliable platform for researchers to study the functional implications of PNRC1 gene disruption, enabling the elucidation of its biological pathways and potential involvement in diseases.
The mechanism behind these knockout cell lines is rooted in targeted gene editing, which effectively disables the PNRC1 gene, allowing researchers to observe the resulting phenotypic changes and cellular responses. This action opens avenues to investigate the gene’s role in critical functions such as cell proliferation, differentiation, and apoptosis, ultimately aiding in the understanding of broader biological and pathological contexts.
The scientific importance of PNRC1 Gene Knockout Cell Lines cannot be overstated, with applications spanning from basic academic research to translational research in clinical settings. They serve as vital tools in the study of cancer biology, neurodegenerative disorders, and various other diseases where RNA processing plays a critical role, facilitating the testing of therapeutic interventions and genetic interactions.
One of the standout advantages of PNRC1 Gene Knockout Cell Lines is their specificity and precision. Unlike overexpression models, these knockout cell lines enable the observation of gene loss effects without the confounding influences of overexpressed gene products. Moreover, they are validated and backed by rigorous quality control, ensuring consistency and reliability in experimental results.
For researchers and clinicians alike, the value of utilizing PNRC1 Gene Knockout Cell Lines lies in their potential to drive innovation in genetic research and therapeutic development. These models offer a comprehensive view into the consequences of gene disruption, paving the way for novel discoveries and advancements in treatment strategies.
Our company is dedicated to supplying high-quality biological products that empower scientific research and discovery. Our expertise in genetic engineering and commitment to providing reliable tools make us a trusted partner in your research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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