Gene: PNMA2
Official Full Name: PNMA family member 2provided by HGNC
Gene Summary: Predicted to be involved in positive regulation of apoptotic process. Predicted to be located in nucleolus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31615 | PNMA2 Knockout cell line (HeLa) | Human | PNMA2 | 1:3~1:6 | Negative | Online Inquiry |
KO31616 | PNMA2 Knockout cell line (HEK293) | Human | PNMA2 | 1:3~1:6 | Negative | Online Inquiry |
KO31617 | PNMA2 Knockout cell line (A549) | Human | PNMA2 | 1:3~1:4 | Negative | Online Inquiry |
PNMA2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the PNMA2 gene. This gene has been implicated in various neurological disorders, making its study essential for understanding disease mechanisms and potential therapeutics. The creation of these knockout cell lines allows researchers to observe the functional consequences of PNMA2 gene deletion, enabling the investigation of its role in cellular pathways and neurological functions.
Key functions of the PNMA2 Knockout Cell Lines include studying cellular stress responses and neuroprotection mechanisms. By utilizing CRISPR-Cas9 gene editing technology, these cell lines exhibit high specificity and efficiency in targeting the PNMA2 gene, allowing for precise analysis of altered cellular behaviors, signaling pathways, and phenotypic changes. Researchers can utilize these models to elucidate the molecular interactions involved in neurodegenerative diseases, thereby shedding light on potential biomarkers and therapeutic targets.
The scientific importance of PNMA2 Knockout Cell Lines cannot be overstated, as they serve as valuable tools in both basic and translational research settings. Their applications range from drug discovery to understanding the etiology of neurodegenerative conditions such as Alzheimer's disease and multiple sclerosis. In clinical research, these cell lines facilitate the high-throughput screening of compounds that may modulate PNMA2-associated pathways, thus accelerating the path toward novel therapeutics.
Compared to alternative models, such as wild-type cell lines or model organisms, PNMA2 Knockout Cell Lines provide a unique advantage by allowing researchers to specifically dissect the effects of PNMA2 absence in a controlled environment, reducing confounding variables inherent in whole-organism studies.
By offering these gene knockout cell lines, our company demonstrates its commitment to advancing scientific understanding and therapeutic innovation. With a focus on quality and reliability in our product offerings, we empower researchers and clinicians to make significant strides forward in the quest for effective treatments and comprehensive insights into neurological disorders.
Please note that all services are for research use only. Not intended for any clinical use.
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