Gene: PLXNC1
Official Full Name: plexin C1provided by HGNC
Gene Summary: This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO32227 | PLXNC1 Knockout cell line (HEK293) | Human | PLXNC1 | 1:3~1:6 | Negative | Online Inquiry |
PLXNC1 Gene Knockout Cell Lines are genetically engineered cellular models specifically designed to investigate the role of the PLXNC1 gene in various biological processes. This product features a complete knockout of the PLXNC1 gene, achieved using advanced CRISPR/Cas9 gene-editing technology, ensuring a precise and effective disruption of gene function. By targeting and deactivating the PLXNC1 gene, researchers can explore the resultant phenotypic changes, offering valuable insights into its involvement in cellular signaling pathways, cancer progression, and inflammatory responses.
These cell lines allow researchers to dissect complex biological phenomena by enabling high-throughput screening, drug discovery, and functional genomics studies. The knockout model provides a unique platform for understanding how the absence of the PLXNC1 gene influences cellular behaviors, including adhesion, migration, and immune response. This information is critical not only for basic research but also has potential clinical implications such as identifying novel therapeutic targets for cancer and autoimmune diseases.
Compared to traditional knockdown models, PLXNC1 Gene Knockout Cell Lines deliver several advantages, including irreversible gene disruption, enhanced stability, and reproducibility of results. These attributes make them more reliable for long-term studies and translational research. Additionally, they can serve as a baseline for comparison with other genetically modified lines, facilitating a thorough exploration of PLXNC1-related signaling and interactions.
Researchers and clinicians will find these knockout cell lines invaluable, as they provide a robust framework for examining gene functions with potential applications in personalized medicine and biomarker discovery. Crafting effective therapeutic interventions relying on a clear understanding of gene functions can ultimately enhance patient outcomes.
Our company specializes in providing high-quality biological products, combining state-of-the-art gene-editing techniques with extensive scientific expertise. Our commitment to advancing research through innovation ensures that our customers access products that significantly impact their studies and therapeutic developments.
Please note that all services are for research use only. Not intended for any clinical use.
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